Ethyl 3-bromoisoxazole-5-carboxylate(CAS#105174-97-8)

Introduction

Ethyl 3-bromoisoxazole-5-carboxylate is an organic compound commonly abbreviated as BEF. The following is a description of its nature, use, preparation and safety information:

Nature:

-Appearance: Ethyl 3-bromoisoxazole-5-carboxylate is a colorless or slightly yellow liquid.

-molecular formula: its chemical formula is C7H7BrN2O2. It has a molecular weight of 223.04g/mol.

-Melting Point: Ethyl 3-bromoisoxazole-5-carboxylate has a melting point of about 90°C.

-Solubility: For organic solvents, such as ethanol, acetone and dimethylformamide, it is soluble, but its solubility in water is low.

Use:

-3-bromoisoxazole-5-carboxylic acid ethyl ester is mainly used as a chemical reagent and intermediate. It can be used in organic synthesis reactions, such as the synthesis of drugs, pesticides and dyes containing isoxazole derivatives.

-Due to its potential application in the synthesis of biologically active molecules, it can also be used in the field of drug synthesis and drug research.

Preparation Method:

-3-bromoisoxazole-5-carboxylic acid ethyl ester can be prepared by reacting 3-bromoisoxazole with ethyl formate. The specific preparation method is as follows:

1. 3-Bromoisoxazole and ethyl formate were added to the reaction vessel.

2. Under appropriate conditions, such as at room temperature or after heating, the reactants are weighted and stirred.

3. After a period of time, the reaction will proceed, and finally ethyl 3-bromoisoxazole-5-carboxylate will be obtained.

4. filtration or distillation can be pure.

Safety Information:

-3-bromoisoxazole-5-carboxylic acid ethyl ester should pay attention to protective measures during operation, wear appropriate protective gloves and eye protection equipment.

-It is an organic solvent and has a certain degree of volatility, so it should be operated in a well-ventilated place.

-Avoid direct contact with skin and eyes to avoid irritation and damage.

-During storage and handling, safe operating procedures should be followed to avoid contact with oxygen or other flammable substances to prevent fire or explosion.

-In case of contact or misuse, rinse immediately with plenty of water and seek medical attention.