Ethyl 2-oxopiperidine-3-carboxylate（CAS# 3731-16-6)
| Hazard Symbols | Xn – Harmful |
| Risk Codes | R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 – Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 – Do not breathe dust. S24/25 – Avoid contact with skin and eyes. S36 – Wear suitable protective clothing. S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| HS Code | 29337900 |
| Hazard Class | IRRITANT |
Introduction
Ethyl 2-oxopiperidine-3-carboxylate, also known as Ethyl 2-oxopiperidine-3-carboxylate, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: colorless liquid
-Molecular formula: C9H15NO3
-Molecular weight: 185.22g/mol
-Melting point:-20°C
-Boiling point: 267-268°C
-Density: 1.183g/cm³
-Solubility: Soluble in many organic solvents, such as alcohols, ethers and esters.
Use:
-Drug synthesis: In organic synthesis, Ethyl 2-oxopiperidine-3-carboxylate is often used as an intermediate for the synthesis of other compounds. It can be used to synthesize compounds with biological activity, such as drugs, pesticides and biomolecular probes.
-Chemical research: Due to its special structure and reactivity, Ethyl 2-oxopiperidine-3-carboxylate can also be used as a reagent in chemical research.
Preparation Method:
Ethyl 2-oxopiperidine-3-carboxylate can be prepared by the following steps:
1. reacting 3-piperidinecarboxylic acid with an organic solvent such as ethanol to generate ethyl 3-piperidinecarboxylate;
2. Add imino chloride (NH2Cl) and hydrogen peroxide (H2O2) to the reaction system to generate Ethyl 2-oxopiperidine-3-carboxylate.
Safety Information:
- Ethyl 2-oxopiperidine-3-carboxylate is an organic compound and needs to follow basic laboratory safety procedures when used.
-Avoid direct contact with skin and eyes, and prevent inhalation or swallowing.
-should be stored in a cool, dry, well-ventilated place, away from fire and oxidizing agents.
-Avoid dust or contact with oxidants, acids, alkalis and other substances during handling or storage to prevent dangerous reactions.
Please note that the safe use and handling of Ethyl 2-oxopiperidine-3-carboxylate needs to be evaluated on a case-by-case basis, and follow the corresponding operating procedures and precautions.
