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(E)-Methyl 4-bromocrotonate(CAS# 6000-00-6)

Chemical Property:

Molecular Formula C5H7BrO2
Molar Mass 179.01
Density 1.522g/mLat 25°C(lit.)
Melting Point 83-85℃
Boling Point 83-85°C13mm Hg(lit.)
Flash Point 197°F
Solubility Chloroform (Slightly), Methanol (Slightly)
Appearance Oil
Color Colourless
BRN 1745755
Storage Condition 2-8°C
Refractive Index n20/D 1.501

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 Risk and Safety

Hazard Symbols Xi – Irritant
Risk Codes R37/38 – Irritating to respiratory system and skin.
R41 – Risk of serious damage to eyes
R36/37/38 – Irritating to eyes, respiratory system and skin.
Safety Description S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S39 – Wear eye / face protection.
WGK Germany 3
RTECS GQ3120000
FLUKA BRAND F CODES 8-9
HS Code 29161900

 

Introduction

Trans-4-bromo-2-butenoic acid methyl ester is an organic compound with the chemical formula C6H9BrO2. The following is information about the properties, use, preparation and safety of the compound:Nature:
Trans-4-bromo-2-butenoic acid methyl ester is a colorless liquid with a special smell. It has a density of about 1.49g/cm3, a boiling point of about 171-172°C, and a flash point of about 67°C. It is insoluble in water at room temperature, but it is miscible with organic solvents such as ethanol, ether, etc.

Use:
Trans-4-bromo-2-butenoic acid methyl ester is mainly used as an intermediate in organic synthesis reactions. It can be used for the synthesis of other organic compounds, for example for the synthesis of compounds in medicinal chemistry and pesticide chemistry.

Preparation Method:
Trans-4-bromo-2-butenoic acid methyl ester is usually prepared by bromination reaction and esterification reaction. Butene is first reacted with bromine to give 4-bromo-2-butene, which is then esterified with methanol to give trans-4-bromo-2-butenoic acid methyl ester.

Safety Information:
Trans-4-bromo-2-butenoic acid methyl ester is a kind of organic solvent and chemical raw material, which has certain danger. It is irritating and corrosive, and contact with the skin, eyes or respiratory tract can cause irritation and injury. Direct contact should be avoided during use, and appropriate respiratory protection and protective clothing should be taken. In addition, care should be taken to avoid contact with oxidants and strong acids during storage to prevent dangerous reactions. If you need to use this compound, please operate in a safe facility and follow the relevant safe working procedures.


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