Difluoromethyl 2-pyridyl sulfone (CAS# 1219454-89-3)
2-[(difluoromethyl)sulfonyl]pyridine is an organic compound. The following is an introduction to the properties, uses, preparation methods and safety information of this compound:
Quality:
- Appearance: White crystalline, solid
- Solubility: Soluble in some organic solvents, such as chloroform and dimethyl sulfoxide
Use:
Method:
The preparation method of 2-[(difluoromethyl)sulfonyl]pyridine can be achieved by the following steps:
Acetyl fluoride is prepared first, and acetic acid and hydrogen fluoride are reacted.
The resulting fluoroacetyl chloride is reacted with pyridine to produce 2-Acetylpyridine.
2-Fluoroacetylpyridine is reacted with sulfonyl chloride to form 2-[(difluoromethyl)sulfonyl]pyridine.
Safety Information:
2-[(difluoromethyl)sulfonyl]pyridine has some toxicity and should be handled safely and follow the relevant safety regulations. When using or storing, contact with strong oxidants and strong acids should be avoided to avoid dangerous reactions. Avoid inhaling dust or contact with skin and eyes. When handling this compound, appropriate personal protective equipment such as protective gloves, safety glasses, and a protective face shield should be worn.