D-Ornithine monohydrochloride（CAS# 16682-12-5)

Molecular Formula	C5H13ClN2O2
Molar Mass	168.62
Melting Point	239°C (dec.)(lit.)
Boling Point	308.7°C at 760 mmHg
Specific Rotation(α)	[α]D20 -23.0～-24.5゜ (c=4, HCl)
Flash Point	140.5°C
Solubility	Water (Slightly)
Vapor Presure	0.00015mmHg at 25°C
Appearance	White powder
Color	Off-White
BRN	4153339
Storage Condition	Inert atmosphere,Room Temperature
MDL	MFCD00012917

Product Detail

Safety Description	24/25 – Avoid contact with skin and eyes.
WGK Germany	3
FLUKA BRAND F CODES	3-10
HS Code	29224999

application	ornithine is used to improve athletic performance, reduce the treatment of glutamine poisoning, brain conditions due to liver diseases (hepatic encephalopathy), and is used for wound healing.
preparation	experiment in alkaline solution, DL-ornithine can be obtained by one-pot cooking hydrolysis-racemization reaction of L arginine, and then directly biotransformation with lysine decarboxylase in HafniaalveiAS1.1009 to prepare D-ornithine hydrochloride in a yield of 45.3%. At the same time, putrescine was obtained in a yield of 41.5%. It was determined that L-arginine was reacted into DL-ornithine within 3 hours under reflux condition with 1.0 mol/L sodium hydroxide aqueous solution and 0.10 molar ratio of salicylaldehyde. The results of the study on the properties of lysine decarboxylase in biotransformation show that the specific enzyme activity can be increased to 6 119 U by adding 1mmol/L Fe2 +. Under this optimized condition, the conversion time is 16 h, it provides a new method for the preparation of D-ornithine hydrochloride and putrescine.
biological activity	(R)-Ornithine hydrochloride is an endogenous metabolite.