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D(-)-Glutamic acid（CAS# 6893-26-1) Featured Image
  • D(-)-Glutamic acid（CAS# 6893-26-1) 1

D(-)-Glutamic acid（CAS# 6893-26-1)

Chemical Property:

Molecular Formula C5H9NO4
Molar Mass 147.13
Density 1.5380
Melting Point 200-202°C (subl.)(lit.)
Boling Point 267.21°C (rough estimate)
Specific Rotation(α) -31.3 º (c=10, 2 N HCl)
Flash Point 155.7°C
Water Solubility 7 g/L (20 ºC)
Solubility Water (Slightly)
Vapor Presure 2.55E-05mmHg at 25°C
Appearance White crystal
Color White to off-white
Merck 14,4469
BRN 1723800
pKa pK1:2.162(＋1);pK2:4.272(0);pK3:9.358(－1) (25°C)
Storage Condition Keep in dark place,Sealed in dry,Room Temperature
Refractive Index 1.4210 (estimate)
MDL MFCD00063112
Physical and Chemical Properties White Crystal or crystalline powder; Soluble in water, slightly soluble in ethanol, insoluble in ether; Specific optical rotation [α]20D-30.5 °(0.5-2 mg/mL, 6mol/L HCl),LD50 (human, intravenous) 117 mg/kg.
Use Amino acid drugs.
In vitro study Various d-amino acids, such as D-serine, D-aspartic acid (D-Asp), and D-glutamic acid (D-Glu) are widely found in mammals including human beings and they are now thought to be the candidates of novel physiologically active substances and/or biomarkers. D-[Asp/Glu] (4 mg/mL) inhibits IgE binding (75%) to peanuts while D-Glu, D-Asp has no inhibitory effect. IgE is specific for D-[Asp/Glu] and may have the potential for removing IgE or reducing IgE binding to peanut allergens.
In vivo study D-glutamic acid is currently paid attention as a modulator of neuronal transmission and hormonal secretion. It is metabolized only by D-aspartate oxidase in mammals. After intraperitoneal injection, L-glutamate is catabolized via a-ketoglutarate, whereas D-glutamate is converted to n-pyrrolidone carboxylic acid. Carbon 2 of both D- and L-glutamate is converted in the cecum to the methyl carbon of acetate. Both rat liver and kidney catalyze the conversion of D-glutamic acid to n-pyrrolidone carboxylic acid.

Product Detail

Product Tags

Hazard Symbols Xi – Irritant
Risk Codes 36/37/38 – Irritating to eyes, respiratory system and skin.
Safety Description S24/25 – Avoid contact with skin and eyes.
S36 – Wear suitable protective clothing.
S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany 3
FLUKA BRAND F CODES 10
TSCA Yes
HS Code 29224200

 

Introduction

D-glutenate, also known as D-glutamic acid or sodium D-glutamate, is a naturally occurring amino acid with a variety of important properties and uses.

 

The main properties of D-gluten are as follows:

Mild taste: D-gluten is an umami enhancer that enhances the umami taste of foods and enhances the flavor of foods.

Nutritional supplement: D-gluten is one of the essential amino acids for the human body and plays an important role in maintaining human health.

Chemically stable: D-glunine is relatively stable under acidic conditions and can also maintain relative stability under high temperature conditions.

 

Use of D-Gluten Acid:

Biochemical research: D-glutamic acid is widely used in biochemical research and experiments to study its biochemical reactions and metabolic pathways in living organisms.

 

The preparation method of D-gluten is mainly obtained by microbial fermentation or chemical synthesis. Microbial fermentation production is currently the main preparation method, using certain strains to produce a large amount of D-glutamic acid through fermentation. Chemical synthesis generally uses synthetic raw materials and specific reaction conditions to synthesize D-gluten acid.

 

Safety Information of D-Gluten: In general, D-Gluten is safe under conditions of proper use and storage. In addition, for certain populations, such as infants and pregnant women, or those with glutamate sensitivity, it may be more appropriate to use or avoid D-glutamate in moderation.

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