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D-2-Amino-4-methylpentanoic acid(CAS# 328-38-1)

Chemical Property:

Molecular Formula C6H13NO2
Molar Mass 131.17
Density 1.2930 (estimate)
Melting Point >300°C(lit.)
Boling Point 225.8±23.0 °C(Predicted)
Specific Rotation(α) -15.45 º (c=4, 6N HCl)
Flash Point 90.3°C
Water Solubility 24 g/L (25 ºC)
Solubility Aqueous Acid (Sparingly), Water (Slightly)
Vapor Presure 0.0309mmHg at 25°C
Appearance White crystal
Color White
BRN 1721721
pKa 2.55±0.21(Predicted)
Storage Condition Keep in dark place,Inert atmosphere,Room temperature
Refractive Index -15 ° (C=4, 6mol/L H
MDL MFCD00063088
Physical and Chemical Properties White scaly crystal or crystalline powder; Soluble in water and acetic acid, slightly soluble in ethanol, insoluble in ether; pI5.98, heated to 145-147 ℃ to begin sublimation, the decomposition point is 293-295 ℃; Relative density of 1.293, specific rotation [α]20D-10.34 °(0.5-2.0 mg/ml,H2O), [α]20D-15.6 °(0.5-2.0 mg/ml,5 mol/L HCl),LD50 (rat, intraperitoneal) 642 mg/kg.
In vitro study In a screen of candidate neuronal receptors, D-leucine failed to compete for binding by cognate ligands, potentially suggesting a novel target. Even at low doses, D-leucine suppressed ongoing seizures at least as effectively as diazepam but without sedative effects. These studies raise the possibility that D-leucine may represent a new class of anti-seizure agents, and that D-leucine may have a previously unknown function in eukaryotes.

Product Detail

Product Tags

Hazard Symbols Xi – Irritant
Risk Codes 36/37/38 – Irritating to eyes, respiratory system and skin.
Safety Description S22 – Do not breathe dust.
S24/25 – Avoid contact with skin and eyes.
S36 – Wear suitable protective clothing.
S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany 3
RTECS OH2840000
TSCA Yes
HS Code 29224995

 

Introduction

Solubility in water: 24g/l (25°C), slightly soluble in alcohol, insoluble in ether.


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