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D-2-Amino-3-phenylpropionic acid(CAS# 673-06-3)

Chemical Property:

Molecular Formula C9H11NO2
Molar Mass 165.19
Density 1.1603 (rough estimate)
Melting Point 273-276°C(lit.)
Boling Point 293.03°C (rough estimate)
Specific Rotation(α) 33.5 º (c=2, H2O)
Water Solubility 27 g/L (20 ºC)
Solubility Soluble in water, slightly soluble in methanol and ethanol, insoluble in ether
Appearance White crystalline powder
Color White to off-white
Merck 14,7271
BRN 2804068
pKa 2.2(at 25℃)
Storage Condition Store at RT.
Stability Stable. Incompatible with strong oxidizing agents, acids, bases.
Refractive Index 34 ° (C=2, H2O)
MDL MFCD00004270
Physical and Chemical Properties Melting point 273-276°C
specific rotation 33.5 ° (c = 2, H2O)
water-soluble 27g/L (20°C)
Use Used as a pharmaceutical intermediate or API for the synthesis of nateglinide and other drugs

Product Detail

Product Tags

Risk Codes 34 – Causes burns
Safety Description S24/25 – Avoid contact with skin and eyes.
S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
S27 – Take off immediately all contaminated clothing.
S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany 3
RTECS AY7533000
TSCA Yes
HS Code 29224995
Hazard Note Irritant
Toxicity TDLo orl-hmn: 500 mg/kg/5W-I:GIT JACTDZ 1(3),124,82

 

Introduction

D-phenylalanine is a protein raw material with the chemical name D-phenylalanine. It is formed from the D-configuration of phenylalanine, a natural amino acid. D-phenylalanine is similar in nature to phenylalanine, but it has different biological activities.

It can be used as a raw material in medicines, health products and nutritional supplements to improve the function of the central nervous system and regulate chemical balance in the body. It is also used in the synthesis of compounds with antitumor and antimicrobial activities.

 

The preparation of D-phenylalanine can be carried out by chemical synthesis or biotransformation. Chemical synthesis methods typically use enantioselective reactions to obtain products with D configurations. The biotransformation method uses the catalytic action of microorganisms or enzymes to convert natural phenylalanine into D-phenylalanine.

It is an unstable compound that is susceptible to degradation by heat and light. Excessive intake may cause gastrointestinal upset. In the process of using D-phenylalanine, the dosage should be strictly controlled, and relevant safety operating procedures should be followed. For individual people who are allergic to D-phenylalanine or have abnormal phenylalanine metabolism, it should be avoided or used under the guidance of a doctor.


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