Carbamic acid, (3-methylenecyclobutyl)-, 1,1-dimethylethyl ester (9CI)(CAS# 130369-04-9)

1-(Boc-amino)-3-methylenecyclobutane is an organic compound whose structural formula is Boc-NH-CH2-CH2-CH2-CH2. The following is a description of its nature, use, preparation and safety information:

Nature:
1-(Boc-amino)-3-methylenecyclobutane is a colorless solid that is soluble in organic solvents at low temperatures. It has low volatility and high stability.

Use:
1-(Boc-amino)-3-methylenecyclobutane is commonly used as a protecting group in organic synthesis. The Boc protecting group can protect an amino group in an organic synthesis reaction to prevent an unnecessary reaction of the amino group, thereby facilitating synthesis of a target compound. In addition, it can also be used for the synthesis of amides, hydrazones and other compounds.

Preparation Method:
1-(Boc-amino)-3-methylenecyclobutane is usually prepared by reacting Boc-aminobutanol with methylene chloride. The specific operation can refer to the relevant synthetic route in the organic synthesis literature and the experimental manual.

Safety Information:
1-(Boc-amino)-3-methylenecyclobutane is generally safe under normal use and operating conditions, but it still needs to be handled with caution. Since it is an organic compound, direct contact with skin and eyes should be avoided, and protective gloves, safety glasses and external laboratory ventilation equipment should be used during operation. In addition, it should be stored in a closed container and away from fire and oxidizing agents. If a leak occurs, it should be cleaned immediately and prevented from entering the water body or sewer.

Important note: This article is only an introduction to chemical knowledge. If you need to use this compound in a laboratory or industrial environment, please ensure that you comply with relevant safety operating guidelines and regulations, and operate under the guidance of professionals.