Boronic acid B-(5-chloro-2-benzofuranyl)-(CAS# 223576-64-5)
Introduction
5-Chlorobenzofuran-2-boronic acid. The following is an introduction to its properties, uses, manufacturing methods and safety information:
Quality:
- Appearance: White crystalline solid
- Soluble: Soluble in most organic solvents
- Stability: Stable at room temperature, but decomposition may occur at high temperatures or under light
Use:
- It is commonly used in coupling reactions, such as Suzuki coupling reactions, including the synthesis of aromatic compounds and the construction of organic molecules.
- It can also be used as a fluorescent probe and biomarker.
Method:
- 5-Chlorobenzofuran-2-boronic acid can be obtained by the reaction of boric acid with corresponding halogenated aromatic hydrocarbons (e.g., 5-chloro-2-arylfuran).
- The reaction is generally carried out in an inert atmosphere under alkaline conditions.
Safety Information:
- 5-Chlorobenzofuran-2-boronic acid may be irritating to the eyes, skin, and respiratory tract.
- When operating, wear appropriate protective gloves and eye/face protection equipment to ensure that the operation is carried out in a well-ventilated area.
- When storing and handling, avoid contact with strong oxidants and store away from fire.
- In case of accidental splashing into your eyes or skin, rinse immediately with plenty of water and seek medical assistance. In case of accidental inhalation, remove from fresh air immediately and seek medical assistance.