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Boc-L-Serine methyl ester(CAS# 2766-43-0)

Chemical Property:

Molecular Formula C9H17NO5
Molar Mass 219.24
Density 1.082g/mLat 25°C(lit.)
Boling Point 354.3±32.0 °C(Predicted)
Specific Rotation(α) -18 º (c=5 in methanol)
Flash Point >230°F
Water Solubility Slightly soluble in water.
Vapor Presure 1.94E-06mmHg at 25°C
Appearance Pale yellow liquid
Color Colorless to yellow
BRN 3545389
pKa 10.70±0.46(Predicted)
Storage Condition Keep in dark place,Sealed in dry,Room Temperature
Refractive Index n20/D 1.452(lit.)
MDL MFCD00191869

Product Detail

Product Tags

Safety Description S23 – Do not breathe vapour.
S24/25 – Avoid contact with skin and eyes.
WGK Germany 3
HS Code 29241990

 

Introduction

Boc-L-serine methyl ester is an organic compound with the following properties:

 

Appearance: Boc-L-serine methyl ester is a white crystalline solid.

Solubility: Boc-L-serine methyl ester is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and methanol.

Stability: Store in dark conditions, can be stored for a long time.

 

Boc-L-serine methyl ester has a wide range of applications in organic synthesis and is mainly used in the following areas:

 

Peptide synthesis: As an amine protective group, Boc-L-serine methyl ester is often used as a starting material or intermediate for the synthesis of peptide chains, which can effectively protect amino groups and prevent non-specific reactions during the synthesis process.

 

Method for preparing Boc-L-serine methyl ester:

 

Boc-L-serine methyl ester can be obtained by reacting L-serine with methyl formate. The specific reaction steps include: dissolving L-serine in anhydrous methanol, adding a base catalyst and stirring to mix, and then adding methyl formate. After the reaction has been going on for some time, the product can be obtained by crystallization.

 

Safety Information for Boc-L-Serine Methyl Ester:

 

Safe handling: Protective glasses and gloves should be worn during operation. Avoid contact with skin, eyes, and respiratory tract.

Storage Caution: Store in a dark, dry place, away from fire and oxidants.

Toxicity: Boc-L-serine methyl ester is an organic compound with some toxicity. Safe operating procedures should be followed and operated in a well-ventilated area.

Waste disposal: Comply with local regulations for waste disposal and do not discharge liquid or solids into the sewer or environment.

 


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