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BOC-L-Pyroglutamic acid methyl ester (CAS# 108963-96-8)

Chemical Property:

Molecular Formula C11H17NO5
Molar Mass 243.26
Density 1.209±0.06 g/cm3(Predicted)
Melting Point 68-72 °C69-74 °C
Boling Point 361.6±35.0 °C(Predicted)
Flash Point 172.5°C
Solubility Soluble in dichloromethane.
Vapor Presure 2.04E-05mmHg at 25°C
Appearance White crystal
Color White to Almost white
pKa -4.28±0.40(Predicted)
Storage Condition 2-8°C

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Brief introduction
Boc-L-pyroglutamic acid methyl ester is an organic compound, which is commonly used as an intermediate in organic synthesis.

Boc-L-Methyl pyroglutamate is a white or off-white solid soluble in ethanol and dimethylformamide. It has the structure of a standard amino acid with a Boc protecting group on its β-amino acid, which can be removed in organic synthesis reactions.

Boc-L-pyroglutamic acid methyl ester is often used as a protective group in organic synthesis to make it stable during synthesis and then removed by chemical reaction.

The method for the preparation of Boc-L-metaroglutamic acid methyl ester involves reacting pyroglutamic acid with methyl ester and the introduction of a protective group under appropriate conditions. This synthesis method is relatively common in the laboratory.

Safety information: Boc-L-methyl pyroglutamate is generally a low-toxicity compound. Compliance with laboratory safety practices and proper precautions, such as wearing appropriate protective gloves and glasses, and operating in a well-ventilated environment is still required when operating. Any chemical substance used should be properly handled and stored to ensure safety and avoid accidents.


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