Boc-L-Histidine(Tosyl)（CAS# 35899-43-5)
| Safety Description | 24/25 – Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29350090 |
Introduction
N(alpha)-boc-N(im)-tosyl-L-histidine(N(alpha)-boc-N(im)-tosyl-L-histidine) is a compound. Here are some information about its nature, use, formulation and safety:
Nature:
-Appearance: White crystalline solid
-Molecular formula: C25H30N4O6S
-Molecular weight: 514.60g/mol
-Melting point: 158-161 degrees Celsius
-Solubility: Soluble in alcohols, ketones and some organic solvents
Use:
- N(alpha)-boc-N(im)-tosyl-L-histidine can be used as a protecting group to protect the histidine functional group during peptide synthesis.
-In peptide chemistry, it can be used as a precursor compound for the synthesis of biologically active polypeptides.
Preparation Method:
The preparation of N(alpha)-boc-N(im)-tosyl-L-histidine is relatively complex and requires a series of chemical steps. A common preparation method is to react tert-butyl chloroformate with L-histidine imidazole ester, and then react with methylbenzenesulfonyl chloride to obtain the target product.
Safety Information:
- N(alpha)-boc-N(im)-tosyl-L-histidine may be irritating and sensitizing to humans.
-During handling and storage, it is recommended to take appropriate personal protective measures, such as wearing gloves, goggles and protective clothing.
-Avoid contact with skin, eyes and respiratory tract, and maintain a well-ventilated laboratory environment.
-When using and disposing of this compound, relevant safety procedures and regulations should be followed.
