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Boc-L-Glutamic acid 1-benzyl ester(CAS# 30924-93-7)

Chemical Property:

Molecular Formula C17H23NO6
Molar Mass 337.37
Density 1?+-.0.06 g/cm3(Predicted)
Melting Point 95.0 to 99.0 °C
Boling Point 522.6±50.0 °C(Predicted)
Solubility Chloroform (Slightly), Methanol (Slightly)
Appearance Solid
Color White
BRN 2482076
pKa 4.48±0.10(Predicted)
Storage Condition Sealed in dry,Store in freezer, under -20°C
Refractive Index -30 ° (C=0.7, MeOH)
MDL MFCD00065568
Use Boc-Glu-OBzl is an N-terminal protective amino acid used in solid phase polypeptide synthesis (SPPS) so that the only peptide contains benzyl glutamate residues.

Product Detail

Product Tags

Safety Description 24/25 – Avoid contact with skin and eyes.
WGK Germany 3
HS Code 29242990

 

Introduction

Boc-L-Glutamic acid 1-benzyl ester(Boc-L-Glutamic acid 1-benzyl ester) is an organic compound with a chemical formula of C17H19NO6 and a relative molecular mass of 337.34. It is a white solid, soluble in organic solvents such as ethanol, dimethylformamide and chloroform.

 

Boc-L-Glutamic acid 1-benzyl ester is commonly used in the synthesis of peptide compounds. It can be used as a micellar agent or a protecting group to protect the amino acid group to prevent unwanted side reactions in the chemical reaction, and at the same time can improve the yield. In addition, it can also be used for the synthesis of polypeptide drugs and related bioactive molecules.

 

The method for preparing Boc-L-Glutamic acid 1-benzyl ester is generally to introduce the Boc protecting group into the amino group of glutamic acid, and to carry out esterification reaction with benzyl anhydride ester at this position. The reaction is generally carried out under neutral or basic conditions and usually requires a certain amount of time to ensure completion of the reaction. The product obtained can be purified by crystallization or further purification steps.

 

Regarding safety information, the specific safety of Boc-L-Glutamic acid 1-benzyl ester requires further research and evaluation. However, as a chemical agent, it may have a certain irritation and toxicity. Appropriate laboratory procedures must be followed during contact or use, and appropriate safety precautions must be taken, including the wearing of personal protective equipment (e. G., lab gloves, lab glasses, etc.). During use or disposal, waste should be properly disposed of to avoid environmental pollution.


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