Boc-L-aspartic acid 1-benzyl ester（CAS# 30925-18-9)
| Safety Description | 24/25 – Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29242990 |
Introduction
Boc-Asp-OBzl(Boc-Asp-OBzl) is a compound that has the following properties:
1. Appearance: White crystalline solid.
2. Molecular formula: C24H27N3O7.
3. Molecular weight: 469.49g/mol.
4. Melting point: about 130-134 ° C.
Boc-Asp-OBzl are widely used in biochemistry and synthetic organic chemistry, often used in the synthesis of peptides, proteins and drugs, with the following uses:
1. Peptide synthesis: As a part of the protecting group (Boc protecting group), the amino group in the aspartic acid amino acid can be protected.
2. Drug research: for the synthesis of peptide drugs with anti-inflammatory, anti-tumor and immune regulation activity.
3. Enzyme reaction: Boc-Asp-OBzl can be used for enzyme catalyzed reaction substrate.
The method of preparing the Boc-Asp-OBzl is as follows:
Aspartic acid and benzoyl chloride are esterified to form tert-butoxycarbonyl-aspartic acid benzyl ester (Boc-Asp-OMe), which is subsequently reacted with sodium hexoxide to obtain an intermediate in the form of N-hexanoate. Finally, it undergoes a benzoylation reaction to produce Boc-Asp-OBzl.
Pay attention to the following safety information when using the Boc-Asp-OBzl:
1. The compound may cause irritation and allergic reactions to the human body, and direct contact with skin and eyes should be avoided.
2. Appropriate personal protective measures should be taken during operation, such as wearing gloves and goggles.
3. Keep dry and sealed during storage, and keep away from fire and oxidant.
4. When using and handling Boc-Asp-OBzl, please follow the correct laboratory operating procedures and safe operation.
Please note that when using Boc-Asp-OBzl or any chemicals, you must strictly follow the corresponding safety operation guidelines, and carry out personal protection and risk assessment according to the actual situation.
