BOC-HIS(DNP)-OH（CAS# 25024-53-7)
| Safety Description | S22 – Do not breathe dust. S24/25 – Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 8 |
| TSCA | Yes |
Introduction
(S)-2-((tert-butoxycarbonyl)amino)-3-(1-(2,4-dinitrophenyl)-1H-imidazol-4-yl)propionic acid, often abbreviated as TBNPA. The following is an introduction to the nature, use, preparation and safety information of TBNPA:
Quality:
TBNPA is a colorless to light yellow crystalline or powdered solid. It is almost insoluble in water at room temperature and slightly soluble in some organic solvents such as ethanol and ether. TBNPA is stable in air, but may degrade under the action of high temperatures and ultraviolet light.
Use:
TBNPA is widely used as a flame retardant in plastics, adhesives, coatings, and polymers. It has excellent flame retardant properties and plays an important role in fire prevention. TBNPA can also be used as a fire resistance agent for textiles and polymeric fibers.
Method:
The preparation of TBNPA is usually achieved by chemical reactions. A common method is to react 2,4-dinitroaniline with (S)-2-[(tert-butoxycarbonyl)amino]-3-(1H-imidazol-4-yl)propionic acid, and then remove the protective group to obtain the target product.
Safety Information:
The relevant safety evaluation of TBNPA has shown that it has low toxicity, but the necessary safety practices should still be followed. Direct contact with skin and eyes should be avoided when using and a well-ventilated working environment should be maintained. Personal protective equipment such as appropriate protective gloves and goggles should be worn during handling. In case of any accident or discomfort, seek medical attention immediately.
