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Boc-D-Serine methyl ester(CAS# 95715-85-8)

Chemical Property:

Molecular Formula C9H17NO5
Molar Mass 219.24
Density 1.08g/mLat 25°C(lit.)
Boling Point 215°C(lit.)
Flash Point >230°F
Solubility Chloroform, Methanol
Vapor Presure 1.94E-06mmHg at 25°C
Appearance Liquid
Color Colorless to yellow
pKa 10.70±0.46(Predicted)
Storage Condition Keep in dark place,Sealed in dry,Room Temperature
Refractive Index n20/D 1.453(lit.)

Product Detail

Product Tags

Risk Codes 36/37/38 – Irritating to eyes, respiratory system and skin.
Safety Description S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany 3
HS Code 29241990

 

Introduction

N-(tert-butoxycarbonyl)-D-serine methyl ester is an organic compound with a chemical formula of C11H19NO6 and a molecular weight of 261.27. It is a colorless crystalline solid.

 

Nature:

N-(tert-butoxycarbonyl)-D-serine methyl ester is a stable compound, soluble in organic solvents such as chloroform and dimethylformamide, and insoluble in water. It is an odorless compound.

 

Use:

N-(tert-butoxycarbonyl)-D-serine methyl ester is widely used as a protecting group in chemical synthesis. It can protect the hydroxyl function of serine (Ser) in the synthesis of polypeptides and proteins. If desired, the protecting group can be removed with acid or enzyme to obtain the individual serine.

 

Preparation Method:

N-(tert-butoxycarbonyl)-D-serine methyl ester is usually prepared by adding tert-butoxycarbonyl chloroformic acid (tert-butoxycarbonyl chloride) to the reaction of D-serine methyl ester (D-serine methyl ester). After the reaction, the product is obtained and purified by crystallization.

 

Safety Information:

N-(tert-butoxycarbonyl)-D-serine methyl ester is generally a relatively safe compound under routine experimental operating conditions. However, it is still a chemical substance and should follow laboratory safety procedures. It is recommended to wear appropriate personal protective equipment, such as laboratory glasses, gloves and laboratory coats.


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