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BOC-D-Pyroglutamic acid(CAS# 160347-90-0)

Chemical Property:

Physico-chemical Properties

Molecular Formula C10H15NO5
Molar Mass 229.23
Density 1.304
Melting Point 111-116℃
Boling Point 425.8±38.0 °C(Predicted)
Water Solubility Slightly soluble in water.
pKa 3.04±0.20(Predicted)
Storage Condition 2-8°C
Sensitive Moisture Sensitive
Physical and Chemical Properties Storage Conditions: Store at RT

Product Detail

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Risk and Safety

Hazard Symbols Xi – Irritant
Risk Codes 36 – Irritating to the eyes
Safety Description 26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany 3

BOC-D-Pyroglutamic acid(CAS# 160347-90-0) Introduction

BOC-D-PYR-OH is an organic compound, commonly abbreviated as Boc-D-Phe-OH. The following is an introduction to its nature, use, preparation and safety information:1. Nature:
-Appearance: White crystalline solid.
-molecular formula: C15H23NO4.
-Molecular weight: 281.36g/mol.
-Melting point: 70-72 ℃.
-Stable at room temperature, but will decompose at high temperature.2. Use:
- BOC-D-PYR-OH is an important intermediate for the synthesis of D-pyroglutamic acid derivatives. It is commonly used in the synthesis of peptide drugs, peptide hormones and bioactive peptides.

3. Preparation method:
- BOC-D-PYR-OH can be prepared by the following steps:
a. Pyroglutamic acid is reacted with tert-butyl alcohol and dimethylformamide under suitable temperature conditions to generate.
B. Obtain the target product by crystallization and purification steps.

4. Safety Information:
-Because there is no clear risk data, standard laboratory safety practices should be followed when handling this compound, including wearing personal protective equipment such as lab gloves, wear protective clothing for safety glasses and outside laboratory experiments involving bulk handling.
-In theory, this compound is an in vivo elimination product and may be less toxic to humans. However, sufficient risk assessment should be carried out before the experiment, all experimental operations and results should be carefully recorded.

Please note that the above information is for reference only, and the specific operation needs to refer to relevant literature and laboratory safety regulations.


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