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BOC-D-Leucine monohydrate(CAS# 16937-99-8)

Chemical Property:

Molecular Formula C11H21NO4
Molar Mass 231.29
Density 1.061±0.06 g/cm3(Predicted)
Melting Point 85-87°C(lit.)
Boling Point 356.0±25.0 °C(Predicted)
Specific Rotation(α) 25 ° (C=2, AcOH)
Flash Point 169.1°C
Solubility Acetic Acid (Sparingly), DMSO (Slightly), Methanol (Slightly)
Vapor Presure 4.98E-06mmHg at 25°C
Appearance Solid
Color White
BRN 2331060
pKa 4.02±0.21(Predicted)
Storage Condition Keep in dark place,Sealed in dry,Room Temperature
Refractive Index 25 ° (C=2, AcOH)
MDL MFCD00038294
Physical and Chemical Properties Storage Conditions:? 20℃
WGK Germany:3

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Risk and Safety

Safety Description 24/25 – Avoid contact with skin and eyes.
WGK Germany 3
HS Code 29241990

BOC-D-Leucine monohydrate(CAS# 16937-99-8) Introduction

BOC-D-Leucine monohydrate is an organic compound whose chemical name is N-tert-butoxycarbonyl-D-leucine. It is a white crystalline solid with low solubility.BOC-D-Leucine monohydrate is mainly used in the field of organic synthesis. It acts as a protecting group in peptide synthesis, protecting the amino and carboxyl groups of leucine to prevent them from unwanted chemical reactions. In synthetic polypeptides or proteins, the BOC-D-Leucine monohydrate can be easily removed by acid hydrolysis.

The preparation of BOC-D-Leucine monohydrate is usually accomplished by the reaction of leucine with tert-Butyl carbamate. First, leucine is reacted with the tert-Butyl carbamate in an appropriate solvent, and then the tert-Butyl carbamate protecting group is removed using appropriate acidic conditions (such as acidic aqueous solution or acid for dissolution) to give the BOC-D-Leucine monohydrate.

Regarding safety information, BOC-D-Leucine monohydrate is a chemical, attention should be paid to correct handling and storage methods. It may be irritating to the skin, eyes, respiratory system and digestive system. Therefore, care must be taken to wear appropriate protective equipment during use, such as laboratory gloves, goggles and protective masks. In addition, it should be stored in a dry, cool place, away from fire and oxidizing agents. When handling this compound, closely follow the relevant safety practices.


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