BOC-D-GLU-OH（CAS# 34404-28-9)
| Safety Description | 24/25 – Avoid contact with skin and eyes. |
| HS Code | 29225090 |
Introduction
D-Glutamic acid, N-[(1,1-dimenthylethoxy) carbonyl]-is an organic compound with the chemical structure of C11H19NO6. The following is a detailed description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless to white solid
-Melting point: approx. 125-128°C
-Solubility: Soluble in common solvents
-Chemical properties: It is a stable compound that is not easy to react under common conditions.
Use:
- D-Glutamic acid is an amino acid and is one of the components of proteins in organisms. The protecting group of the N-tert-butoxycarbonyl group can serve to protect the glutamic acid functional group during synthesis and is used in organic synthesis.
-It can also be used in the field of peptide synthesis and protein chemical synthesis, as a synthetic intermediate with special functions.
Preparation Method:
- D-Glutamic acid, N-[(1,1-dimenthylethoxy) carbonyl]-usually synthesized by N-protecting glutamic acid molecules. The specific preparation method can be used to synthesize the intermediate of tert-butyl dimethyl azide by chlorooxide, and then deprotect under the condition of acid catalysis formed by silicate to obtain D-Glutamic acid, N-[(1,1-dimethoxy) carbonyl]-.
Safety Information:
- D-Glutamic acid, N-[(1,1-dimenthylethoxy) carbonyl]-is considered to be low toxic under normal conditions, but it still needs to follow laboratory safety procedures.
-Avoid direct exposure to sensitive areas such as skin, eyes and mucous membranes during handling and use.
-Avoid contact with oxidants and strong acids during storage and handling.
-In case of accidental ingestion or exposure, seek immediate medical assistance.
