BOC-ASP(OBZL)-ONP（CAS# 26048-69-1)

 BOC-ASP(OBZL)-ONP（CAS# 26048-69-1) Introduction

4-Benzyl1-(4-nitrophenyl)(tert-butoxycarbonyl)-L-aspartic acid is an organic compound. The following describes its properties, applications, manufacturing methods, and safety information.

Quality:

- Appearance: Usually white crystals or crystalline powder.

- Solubility: Soluble in some organic solvents such as methanol, methylene chloride and ethanol.

Use:

- It can be used as an amino acid protecting group for the synthesis of peptide sequences.

- Boc-L-Aspartic Acid 4-Benzyl 1-(4-Nitrophenyl)Ester can also be used to construct new bioactive molecules.

Method:

The preparation of 4-benzyl1-(4-nitrophenyl)(tert-butoxycarbonyl)-L-aspartic acid typically includes the following steps:

L-aspartic acid is esterified with Branstri chloride (Boc) to form Boc-L-aspartic acid.

Boc-L-aspartic acid is reacted with benzyl alcohol to produce 4-benzyl Boc-L-aspartic acid.

Under alkaline conditions, 4-benzyl Boc-L-aspartic acid is reacted with excess 4-nitrophenyl iodide to generate 4-benzyl1-(4-nitrophenyl)Boc-L-aspartic acid.

The target product, 4-benzyl1-(4-nitrophenyl)(tert-butoxycarbonyl)-L-aspartic acid, was obtained by deprotecting 4-benzyl1-(4-nitrophenyl)(tert-butoxycarbonyl)-L-aspartic acid by deprotecting (removing the Boc protecting group).

Safety Information:

- There is little safety data for this compound, but as an organic compound, care should be taken to prevent inhalation, skin contact, and ingestion.

- Appropriate personal protective equipment such as laboratory gloves, goggles, and protective masks should be worn during handling.

- It should be operated in a well-ventilated area to avoid the generation of dust.