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8-bromo-1 6-naphthyridin-5(6H)-one (CAS# 155057-97-9)

Chemical Property:

Molecular Formula C8H5BrN2O
Molar Mass 225.04
Density 1.762±0.06 g/cm3(Predicted)
Melting Point 247-251 °C(Solv: water (7732-18-5))
Boling Point 451.1±45.0 °C(Predicted)
Flash Point 226.64°C
Vapor Presure 0mmHg at 25°C
pKa 9.47±0.40(Predicted)
Storage Condition Room Temprature
Sensitive Irritant
Refractive Index 1.665

Product Detail

Product Tags

8-bromo-1, 6-naphythyridin-5 (6h)-one is an organic compound with the molecular formula C13H8BrNO, which is a powdery solid substance.

The properties of this compound are:

1. Appearance: 8-bromo-1, 6-naphythyridin-5 (6h)-one is white or light yellow crystal powder.
2. Melting Point: has a high melting point, about 206-210 ℃.
3. Solubility: It has good solubility in some organic solvents (such as chloroform, acetone and dimethyl sulfoxide).

It has many applications in the laboratory and industry:

1. Chemical reagents: can be used as reagents in organic synthesis reactions, such as applications in the synthesis of drugs and pesticides.
2. Photosensitive material: due to the special nature of its molecular structure, it can be used for the preparation of photosensitive materials.
3. Organic synthesis intermediates: can be used as intermediates for the synthesis of other compounds.

Regarding the preparation method, 8-bromo-1,6-naphthyridin-5(6h)-one can be prepared by the following steps:

1. First, 1,6-naphthoketone is reacted with hydrogen bromide. The reaction conditions may be carried out by heating in the presence of acetic acid.
2. The reaction product is 8-bromo -1,6-naphthoketone, further processing:
a. 8-bromo -1,6-naphthoketone is reacted with pyridine under acid catalysis.
B. Reaction conditions are Reflux reaction, usually in acetic acid.
c. The product obtained by the reaction is 8-bromo-1,6-naphthyridin-5(6h)-one.

Regarding safety information, 8-bromo-1,6-naphthyridin-5(6h)-one is an organic compound, so appropriate safety measures need to be taken:

1. Avoid contact with skin and eyes, such as contact, should immediately rinse with plenty of water.
2. Use should be carried out in a well-ventilated place to avoid inhaling its dust.
3. Should be stored away from the fire and oxidant.
4. Follow proper laboratory procedures and personal protective measures.


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