6-Methyl coumarin（CAS#92-48-8）
| Hazard Symbols | Xn – Harmful |
| Risk Codes | R22 – Harmful if swallowed R42/43 – May cause sensitization by inhalation and skin contact. |
| Safety Description | S22 – Do not breathe dust. S36/37 – Wear suitable protective clothing and gloves. S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| WGK Germany | 3 |
| RTECS | GN7792000 |
| TSCA | Yes |
| HS Code | 29321900 |
| Toxicity | The acute oral LD50 value in rats was reported to be 1.68 g/kg (1.43-1.93 g/kg) (Moreno, 1973). The acute dermal LD50 value in rabbits exceeded 5 g/kg (Moreno, 1973). |
Introduction
6-Methylcoumarin is an organic compound. It is a colorless crystalline solid with an aromatic fruity taste. The following is an introduction to some of the properties, uses, preparation methods and safety information of 6-methylcoumarin:
Quality:
- Appearance: Colorless crystalline solid
- Storage conditions: It is advisable to store in a cool, dry place, away from direct sunlight and high temperatures
Use:
Method:
There are several ways to prepare 6-methylcoumarin, and the following is one of the common synthetic routes:
Coumarin reacts with acetic anhydride to form ethyl vanillin.
Coumarin acetate reacts with methanol to form 6-methylcoumarin under the action of alkali.
Safety Information:
6-Methylcoumarin is generally considered safe under normal use
- Avoid contact with eyes and skin, and rinse immediately with plenty of water if inadvertently touched.
- Avoid inhaling dust or vapours and wear personal protective equipment such as masks and gloves when operating.
- Do not eat and keep out of reach of infants and pets. If accidentally ingested, seek medical attention immediately.
