5-Fluoro-2-nitrotoluene（CAS# 446-33-3)
| Risk Codes | R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 – Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 – Wear suitable protective clothing. S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S37 – Wear suitable gloves. S28A - |
| UN IDs | UN 2811 |
| WGK Germany | 3 |
| HS Code | 29049085 |
| Hazard Note | Irritant |
| Hazard Class | 6.1 |
| Packing Group | III |
Introduction
5-Fluoro-2-nitrotoluene is an organic compound. The following is an introduction to its properties, uses, manufacturing methods and safety information:
Quality:
- Appearance: 5-fluoro-2-nitrotoluene is colorless or yellowish crystal.
- Chemical properties: 5-fluoro-2-nitrotoluene has good chemical stability and is not easy to volatile.
Use:
- Chemical intermediates: 5-fluoro-2-nitrotoluene can be used as an intermediate in organic synthesis for the synthesis of other organic compounds.
Method:
5-Fluoro-2-nitrotoluene can be synthesized by:
Under alkaline conditions, 2-chlorotoluene was reacted with hydrogen fluoride to obtain 5-fluoro-2-chlorotoluene, and then reacted with nitric acid to obtain the target product 5-fluoro-2-nitrotoluene.
In the presence of alcohol, 2-nitrotoluene is reacted with hydrogen bromide, then reacted with hydrogen fluoride, and finally the product is prepared by dehydration.
Safety Information:
- 5-Fluoro-2-nitrotoluene is a chemical that is harsh to the skin and eyes, so wear protective gloves and goggles to avoid direct contact.
- Attention should be paid to fire and explosion prevention measures during use and handling, and avoid contact with open flames, high temperatures or other fire sources.
- Please store and transport properly, away from oxidants and combustibles.
- In case of ingestion or inhalation, seek medical attention immediately and provide information about the chemical.
