5-Chloro-2-hydroxy-3-nitropyridine(CAS# 21427-61-2)
Risk Codes | R36/37/38 – Irritating to eyes, respiratory system and skin. R41 – Risk of serious damage to eyes R37/38 – Irritating to respiratory system and skin. R22 – Harmful if swallowed |
Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection. S39 – Wear eye / face protection. S36 – Wear suitable protective clothing. S37 – Wear suitable gloves. |
WGK Germany | 3 |
HS Code | 29337900 |
Hazard Class | IRRITANT |
Introduction
Properties: It has low solubility in water and good solubility in organic solvents. Its chemical properties are active and it is prone to reduction, alkylation and other reactions.
Use:
2-hydroxy-3-nitro-5-chloropyridine has certain application value in organic synthesis. It can be used as an important intermediate in organic synthesis and is involved in many organic synthesis reactions, such as the synthesis of hop flavor compounds.
Method:
There are many methods for the preparation of 2-hydroxy-3-nitro-5-chloropyridine, the common method is obtained by nitrification of 2-azacyclopentadiene, and then further hydrogenation and chlorination reactions to obtain the target product.
Safety Information:
Avoid contact with strong oxidants, strong acids, strong alkalis and other substances to avoid violent reactions.
Pay attention to protective measures during use, and wear appropriate personal protective equipment, such as safety gloves, goggles, etc.
When using or storing, keep 2-hydroxy-3-nitro-5-chloropyridine in a cool, well-ventilated place, away from fire and high temperatures.