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5-Chloro-2-hydroxy-3-nitropyridine(CAS# 21427-61-2)

Chemical Property:

Molecular Formula C5H3ClN2O3
Molar Mass 174.54
Density 1.61±0.1 g/cm3(Predicted)
Melting Point 232-236 °C
Boling Point 284.1±40.0 °C(Predicted)
Flash Point 125.6°C
Vapor Presure 0.00303mmHg at 25°C
Appearance Solid
BRN 383852
pKa 6.31±0.10(Predicted)
Storage Condition under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index 1.602
MDL MFCD00114884

Product Detail

Product Tags

Risk Codes R36/37/38 – Irritating to eyes, respiratory system and skin.
R41 – Risk of serious damage to eyes
R37/38 – Irritating to respiratory system and skin.
R22 – Harmful if swallowed
Safety Description S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
S39 – Wear eye / face protection.
S36 – Wear suitable protective clothing.
S37 – Wear suitable gloves.
WGK Germany 3
HS Code 29337900
Hazard Class IRRITANT

 

Introduction

 

Properties: It has low solubility in water and good solubility in organic solvents. Its chemical properties are active and it is prone to reduction, alkylation and other reactions.

 

Use:

2-hydroxy-3-nitro-5-chloropyridine has certain application value in organic synthesis. It can be used as an important intermediate in organic synthesis and is involved in many organic synthesis reactions, such as the synthesis of hop flavor compounds.

 

Method:

There are many methods for the preparation of 2-hydroxy-3-nitro-5-chloropyridine, the common method is obtained by nitrification of 2-azacyclopentadiene, and then further hydrogenation and chlorination reactions to obtain the target product.

 

Safety Information:

Avoid contact with strong oxidants, strong acids, strong alkalis and other substances to avoid violent reactions.

Pay attention to protective measures during use, and wear appropriate personal protective equipment, such as safety gloves, goggles, etc.

When using or storing, keep 2-hydroxy-3-nitro-5-chloropyridine in a cool, well-ventilated place, away from fire and high temperatures.

 


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