5-Chloro-2-fluoro-3-methylpyridine（CAS# 375368-84-6)
| Hazard Symbols | Xn – Harmful |
| Risk Codes | R22 – Harmful if swallowed R37/38 – Irritating to respiratory system and skin. R41 – Risk of serious damage to eyes |
| Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 – Wear eye / face protection. |
Introduction
It is an organic compound with the formula C6H5ClFN. It is a colorless liquid with a special smell. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: colorless liquid
-Odor: Special odor
-Density: 1.36 g/mL
-Boiling point: 137-139 ℃
-Melting point:-4 ℃
-Solubility: Miscible with organic solvents, almost insoluble in water.
Use:
It is widely used in organic synthesis and can be used as a catalyst or raw material. It has important applications in the synthesis of pesticides, pharmaceuticals and chemicals, and is commonly used in the manufacture of pesticides, dyes, solvents, etc.
Preparation Method: The preparation method of
is more complicated. A general preparation method is to obtain 5-chloro -2-oxo -3-methyl pyridine by chloro-propionaldehyde reaction through pyridine as raw material, and obtain the final product through fluorination reaction.
Safety Information:
It is an organic compound, and the following safety precautions should be paid attention to when using it:
-Toxicity may result from inhalation, contact or ingestion. Direct contact with skin, eyes and mucous membranes should be avoided.
-Wear appropriate protective equipment such as gloves, goggles and protective clothing when used.
-Avoid contact with oxidants, strong acids, strong bases and other substances to avoid unsafe reactions.
-When leakage occurs, appropriate measures should be taken to clean up the leakage and avoid entering the drainage system and the environment.
When using the compound, take corresponding safety measures according to the actual situation and refer to the safety data sheet of the compound.
