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5-Chloro-2-cyanopyridine(CAS# 89809-64-3)

Chemical Property:

Molecular Formula C6H3ClN2
Molar Mass 138.55
Density 1.33±0.1 g/cm3(Predicted)
Melting Point 106-108℃
Boling Point 110°C/3mmHg(lit.)
Flash Point 98.5°C
Solubility Methanol
Vapor Presure 0.0403mmHg at 25°C
Appearance Bright yellow crystal
Color Yellow Cyrstalline
pKa -2.60±0.10(Predicted)
Storage Condition Inert atmosphere,Room Temperature
Refractive Index 1.565
MDL MFCD03788835

Product Detail

Product Tags

Risk Codes 36/37/38 – Irritating to eyes, respiratory system and skin.
Safety Description S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 – Wear suitable protective clothing.
UN IDs UN 3439 6.1/PG III
HS Code 29333990
Hazard Note Toxic
Hazard Class 6.1
Packing Group III

 

Introduction

5-Chloro-2-cyanopyridine is an organic compound with the chemical formula C6H3ClN2. The following is a description of its nature, use, formulation and safety information:

 

Nature:

-Appearance: 5-Chloro-2-cyanopyridine is a colorless to pale yellow crystalline solid.

-Melting point: Its melting point is 85-87°C.

-Solubility: Good solubility in common organic solvents.

 

Use:

- 5-Chloro-2-cyanopyridine is often used as an intermediate compound in organic synthesis.

-It is an important raw material for the synthesis of compounds such as drugs, pesticides and dyes.

-It can also be used as a substrate for organic synthesis catalysts.

 

Preparation Method:

- 5-Chloro-2-cyanopyridine can be obtained by chlorinating 2-cyanopyridine.

-The reaction is usually carried out under alkaline conditions to improve the reaction efficiency.

-Generally, a reagent such as stannous chloride or antimony chloride is used as a chlorinating agent in the reaction.

 

Safety Information:

- 5-Chloro-2-cyanopyridine is irritating and should be rinsed with water immediately when in contact with skin or eyes.

-When operating, wear appropriate protective gloves and goggles to ensure safety.

-The compound should be kept away from fire and high temperature to prevent fire and explosion.

-It should be stored in a sealed container and away from oxidants and strong acids.

 

Please note that this is only a general introduction, specific use should also refer to the relevant chemical literature and safety data sheets.


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