5-bromo-3-cyanopyridine（CAS# 35590-37-5)
| Risk Codes | R36/37/38 – Irritating to eyes, respiratory system and skin. R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 – Wear suitable protective clothing. S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection. |
| UN IDs | 3276 |
| WGK Germany | 3 |
| HS Code | 29333990 |
| Hazard Note | Irritant |
| Hazard Class | 6.1 |
| Packing Group | III |
Introduction
5-bromo-3-cyanopyridine is an organic compound with the chemical formula C6H3BrN2. It is a white to yellowish crystal, soluble in some organic solvents such as ethanol and dimethyl sulfoxide. The following is a detailed description of the properties, uses, preparation and safety information of 5-bromo-3-cyanopyridine:
Nature:
-Appearance: White to yellowish crystals
-Melting point: approximately 89-93°C
-Boiling point: about 290-305°C
-Density: Approximately 1.64 g/mL
-Molecular weight: 174.01g/mol
Use:
5-bromo-3-cyanopyridine is often used as an intermediate in organic synthesis, and has important applications in the fields of drug synthesis, pesticide synthesis and dye synthesis.
Specific applications include:
-In the field of medicine, it can be used to synthesize anti-tumor drugs, antiviral drugs and antibacterial drugs.
-In the field of pesticides, it can be used for synthetic pesticides and herbicides.
-In the field of dyes, it can be used to synthesize organic dyes.
Preparation Method:
The preparation method of 5-bromo-3-cyanopyridine can be carried out by the following steps:
1. 3-cyanopyridine reacts with hydrobromic acid under alkaline conditions to generate 5-bromo-3-cyanopyridine.
Safety Information:
The following safety precautions should be taken when using 5-bromo-3-cyanopyridine:
-It is an organic compound that is irritating. Avoid inhaling dust or contacting skin and eyes.
-In use and storage, should follow the safety procedures, wear personal protective equipment, such as gloves and safety glasses.
-Avoid mixing or contact with substances such as strong oxidants and strong acids to prevent dangerous reactions.
-Store in a ventilated place away from open flames and heat sources.
-If inhaled or in contact with skin and eyes, rinse immediately with water. Seek medical help if necessary.
In view of safety issues, the use and handling of 5-bromo-3-cyanopyridine should follow correct laboratory procedures and comply with relevant safety regulations.
