5-BROMO-2 4-DIMETHOXYPYRIMIDINE（CAS# 56686-16-9)
| Safety Description | 24/25 – Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29335990 |
Introduction
5-bromo-2,4-dimethoxypyrimidine is an organic compound with the chemical formula C7H8BrN2O2.
Nature:
5-bromo-2,4-dimethoxypyrimidine is a white crystalline solid with a distinctive odor. It has a density of 1.46 g/mL and a melting point of 106-108°C. It is stable at room temperature, but will decompose when encountering high temperature and bright light.
Use:
5-bromo-2,4-dimethoxypyrimidine is often used as an intermediate in organic synthesis, especially in the preparation of fluorescent dyes and pesticides. It is also used to study pharmacology and medicinal chemistry.
Preparation Method:
The preparation of 5-bromo-2,4-dimethoxypyrimidine can be carried out by various methods. One common method is to react 2,4-dimethoxypyrimidine with hydrogen bromide. The reaction is usually carried out in an inert solvent, such as dimethylformamide or dimethylphosphoramidite, with heating at an appropriate temperature.
Safety Information:
5-bromo-2,4-dimethoxypyrimidine is irritating and corrosive, and may cause burns on contact with skin and eyes. Therefore, wear gloves and goggles when handling, and avoid breathing its dust or vapor. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. In addition, contact with oxidizing agents and strong acids should be avoided during storage to prevent accidental reactions.
