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5-Bromo-2 4-dichloropyrimidine(CAS# 36082-50-5)

Chemical Property:

Molecular Formula C4HBrCl2N2
Molar Mass 227.87
Density 1.781 g/mL at 25 °C (lit.)
Melting Point 29-30 °C (lit.)
Boling Point 128 °C/15 mmHg (lit.)
Flash Point >230°F
Solubility Chloroform (Slightly), Ether (Slightly), Ethyl Acetate (Slightly), Toluene (Slig
Vapor Presure 0.004mmHg at 25°C
Appearance Colorless oily
Specific Gravity 1.781
Color Clear colorless to light yellow
BRN 124441
pKa -4.26±0.29(Predicted)
Storage Condition Inert atmosphere,Room Temperature
Refractive Index n20/D 1.603(lit.)
MDL MFCD00127818
Physical and Chemical Properties Colorless or light yellow liquid
Use It is used as a raw material for the synthesis of trisubstituted pyrimidines by combining nucleophilic substitution reactions and palladium-catalyzed aryl cross-coupling reactions.

Product Detail

Product Tags

Risk Codes R23/24/25 – Toxic by inhalation, in contact with skin and if swallowed.
R34 – Causes burns
R43 – May cause sensitization by skin contact
Safety Description S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S27 – Take off immediately all contaminated clothing.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs UN 3263 8/PG 2
WGK Germany 3
HS Code 29335990
Hazard Note Toxic/Corrosive
Hazard Class 8
Packing Group III

 

Introduction

5-Bromo-2,4-dichloropyrimidine is an organic compound.

 

Quality:

- Appearance: 5-Bromo-2,4-dichloropyrimidine is a white crystalline solid.

- Solubility: 5-Bromo-2,4-dichloropyrimidine has low solubility in water and is soluble in organic solvents such as ethanol and acetone.

 

Use:

- Pesticides: 5-bromo-2,4-dichloropyrimidine can be used as a pesticide component of heterocyclic compounds, mainly for the control of aquatic weeds and broad-spectrum weeds.

 

Method:

The synthesis of 5-bromo-2,4-dichloropyrimidine can be carried out by different methods, a common method is to react 2,4-dichloropyrimidine with bromine. This reaction is generally catalyzed by sodium bromide.

 

Safety Information:

- 5-Bromo-2,4-dichloropyrimidine may decompose at high temperatures, producing toxic hydrogen chloride gas. High temperatures and strong acids should be avoided during handling and storage.

- 5-Bromo-2,4-dichloropyrimidine is irritating to the eyes and skin and must be avoided. Appropriate protective gloves, glasses, and a lab coat should be worn during operation.


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