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5-Bromo-2-3-dichloropyridine CAS 97966-00-2

Chemical Property:

Molecular Formula C5H2BrCl2N
Molar Mass 226.89
Density 1.848±0.06 g/cm3(Predicted)
Melting Point 35-37°C
Boling Point 55-65 C
Flash Point 95.076°C
Vapor Presure 0.084mmHg at 25°C
pKa -3.02±0.10(Predicted)
Storage Condition under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index 1.597

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Risk and Safety

Risk Codes R36/37/38 – Irritating to eyes, respiratory system and skin.
R41 – Risk of serious damage to eyes
R37/38 – Irritating to respiratory system and skin.
R25 – Toxic if swallowed
Safety Description S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S39 – Wear eye / face protection.
Hazard Class IRRITANT

 Introduction

5-bromo-2,3-dichloropyridine is an organic compound with the chemical formula C5H2BrCl2N. The following is a description of the properties, uses, preparation and safety information of this compound:

Nature:
-Appearance: Colorless to light yellow crystal or crystalline powder
-Melting point: 62-65°C
-Boiling point: 248°C
-Density: 1.88g/cm³
-insoluble in water, soluble in organic solvents (such as chloroform, methanol, ether, etc.)

Use:
- 5-bromo-2,3-dichloropyridine is an important intermediate in organic synthesis.
-It can be used to prepare labeled compounds containing gaseous radioactive carbon isotopes.

Preparation Method:
The preparation method of -5-bromo-2,3-dichloropyridine is usually obtained by bromination substitution reaction of 2,3-dichloro-5-nitropyridine. The specific method is to first react 2,3-dichloro-5-nitropyridine with phosphorus trichloride, and then carry out bromination substitution reaction with bromine.

Safety Information:
- 5-bromo-2,3-dichloropyridine is an organic compound and needs to follow safe operating procedures when handling and using.
-It may be irritating to the eyes, skin and respiratory system, so wear goggles, gloves and a mask.
-Please keep it properly, away from fire, heat and oxidant, and avoid contact with strong acid and alkali.
-In case of inhalation or accidental contact, clean the affected area immediately and seek medical help.


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