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5-Amino-2-methoxypyridine(CAS# 6628-77-9)

Chemical Property:

Molecular Formula C6H8N2O
Molar Mass 124.14
Density 1.575
Melting Point 29-31 °C (lit.)
Boling Point 85-90 °C/1 mmHg (lit.)
Flash Point >230°F
Water Solubility Slightly soluble
Solubility Chloroform, Methanol (Slightly)
Vapor Presure 0.00951mmHg at 25°C
Appearance Liquid
Color Yellow-brown or red to very dark red
pKa 4.33±0.10(Predicted)
Storage Condition 2-8°C
Refractive Index n20/D 1.575(lit.)
Physical and Chemical Properties Melting point 29-31 °c. Boiling point 85-90 deg C (133Pa), refractive index of 1.5745.
Use Used as a drug Intermediate

Product Detail

Product Tags

Risk Codes R22 – Harmful if swallowed
R36/37/38 – Irritating to eyes, respiratory system and skin.
Safety Description S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39 – Wear suitable gloves and eye/face protection
S36 – Wear suitable protective clothing.
WGK Germany 3
RTECS US1836000
HS Code 29339900
Hazard Class IRRITANT

 

Introduction

2-Methoxy-5-aminopyridine is an organic compound. The following is an introduction to its nature, use, preparation method and safety information:

 

Quality:

- Appearance: 2-methoxy-5-aminopyridine is a colorless crystalline solid.

- Solubility: Soluble in polar solvents such as water, alcohols and ethers.

- Chemical Properties: 2-Methoxy-5-aminopyridine is an alkaline compound that reacts with acids to form salts.

 

Use:

- 2-Methoxy-5-aminopyridine is widely used in the field of organic synthesis, especially in the synthesis of pharmaceuticals and pesticides.

- In the field of pesticides, it can be used in the preparation of agrochemical products such as insecticides and herbicides.

 

Method:

The preparation methods of 2-methoxy-5-aminopyridine are relatively diverse, and the following is a common preparation method:

2-methoxypyridine is reacted with excess ammonia in an appropriate solvent, and after a certain reaction time, temperature and pH control, the product undergoes crystallization, filtration, washing and other steps to obtain the target product.

 

Safety Information:

- 2-Methoxy-5-aminopyridine is an organic compound, and appropriate precautions should be taken during handling, such as wearing gloves, goggles, and protective clothing.

- When storing and handling, it should be kept away from fire sources and oxidants, and avoid contact with strong acids, strong alkalis and other substances.

- When in contact with skin or eyes, rinse immediately with plenty of water and seek medical attention.


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