5-Amino-2-fluoropyridine（CAS# 1827-27-6)
Risk and Safety
| Hazard Symbols | Xi – Irritant |
| Risk Codes | R36/37/38 – Irritating to eyes, respiratory system and skin. R41 – Risk of serious damage to eyes R37/38 – Irritating to respiratory system and skin. |
| Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection. |
| WGK Germany | 3 |
| HS Code | 29333990 |
| Hazard Note | Irritant |
| Hazard Class | 6.1 |
5-Amino-2-fluoropyridine（CAS# 1827-27-6) Introduction
- 5-Amino-2-fluoropyridine is a white to pale yellow crystal with a special sense of smell.
-It is solid under normal temperature and pressure and has high thermal stability.
- 5-Amino-2-fluoropyridine is almost insoluble in water, but can be dissolved in some organic solvents.
Use:
- 5-Amino-2-fluoropyridine is commonly used as a reagent in organic synthesis to catalyze and promote the progress of chemical reactions.
-It also has some applications in the pharmaceutical field and can be used as intermediates for the synthesis of certain drugs.
-In addition, 5-Amino-2-fluoropyridine can also be used in the electronics and polymer industries.
Method:
- 5-Amino-2-fluoropyridine can be obtained by the reaction of 2-fluoropyridine and ammonia. The reaction is typically carried out in an inert atmosphere, for example under nitrogen.
-During the reaction process, it is necessary to control the reaction temperature and reaction time, and carry out appropriate process optimization to improve the yield and purity.
Safety Information:
- 5-Amino-2-fluoropyridine is an irritating compound, and adequate ventilation and personal protective equipment are necessary during handling and use.
-It may be dangerous at high temperatures or in contact with strong oxidants, so it is necessary to pay attention to fire and explosion prevention measures during storage and handling.
-When handling 5-Amino-2-fluoropyridine, avoid direct contact with skin and eyes, and use protective gloves and goggles if necessary.
-When the compound is accidentally inhaled or ingested, seek medical attention.
