4-(trifluoromethyl)benzonitrile（CAS# 455-18-5)
| Risk Codes | R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed. R11 – Highly Flammable |
| Safety Description | S36/37 – Wear suitable protective clothing and gloves. S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36 – Wear suitable protective clothing. |
| UN IDs | UN 1325 4.1/PG 2 |
| WGK Germany | 3 |
| TSCA | T |
| HS Code | 29269095 |
| Hazard Note | Lachrymatory |
| Hazard Class | 6.1 |
| Packing Group | III |
Introduction
Trifluoromethylbenzonitrile. The following is an introduction to its nature, use, preparation method and safety information:
Quality:
Trifluoromethylbenzonitrile is a colorless liquid with a fragrance. It is less dense and insoluble in water but soluble in many organic solvents. It is stable at room temperature but may decompose when exposed to heat.
Use:
Trifluoromethylbenzonitrile can be used as an intermediate in organic synthesis. In the field of pesticides, it can be used in the synthesis of insecticides and herbicides. It can also be used in the preparation of high-performance polymers and electronic materials.
Method:
The preparation of trifluoromethylbenzonitrile is generally achieved by introducing a trifluoromethyl group into the benzonitrile molecule in the reaction. There can be a variety of specific synthesis methods, such as the reaction of cyano compounds with trifluoromethyl compounds, or the trifluoromethylation reaction of benzonitrile.
Safety Information:
Trifluoromethylbenzonitrile is irritating and corrosive at high concentrations and may cause irritation or damage to the skin, eyes, and respiratory tract upon contact. Precautions should be taken when using, such as wearing appropriate protective gloves and glasses. It should also be operated in a well-ventilated area to avoid inhaling vapors. When handling and storing, safety operating procedures should be followed and kept away from fire and heat sources. If a leak occurs, it should be cleaned and treated in time to avoid entering water bodies and sewers.
