4-(TRIFLUOROMETHYL)-BIPHENYL（CAS# 398-36-7)

The following is a brief description of the nature, use, preparation and safety information of the 4-(Trifluoromethyl)biphenyl:

Nature:
-Appearance: 4-(Trifluoromethyl)biphenyl common form is white solid crystal
-Melting point: about 95-97 ℃ (Celsius)
-Boiling point: about 339-340 ℃ (Celsius)
-Density: about 1.25g/cm³ (g/cm3)
-Solubility: Soluble in common organic solvents such as ethanol, ethers and chlorinated hydrocarbons

Use:
- 4-(Trifluoromethyl)biphenyl can be used as an important intermediate in organic synthesis, widely used in pharmaceutical, pesticide, coating and material science and other fields.
-In drug synthesis, it can be used as a synthetic intermediate for proton pump inhibitors, agonists and non-flavonoid non-steroidal anti-inflammatory drugs.

Preparation Method:
The preparation method of 4-(Trifluoromethyl)biphenyl can be used in many ways in practice. One of the common methods is to react 4-amino biphenyl with trifluoromethylmercury fluoride, and then carry out halogenation reaction and re-obtained amino protection reaction, and finally obtain the target product.

Safety Information:
- 4-(Trifluoromethyl)biphenyl is a chemical and should be handled with care to avoid contact with skin, eyes and respiratory tract.
-Wear appropriate personal protective equipment, including protective glasses, gloves and breathing apparatus, when in use.
-In the process of storage and handling, please follow the relevant safety procedures, and keep it in a dry, well-ventilated place, away from fire and flammable materials.
-In case of any accident or accidental exposure, please consult a doctor or professional immediately, and provide the safety data sheet (SDS) for reference.