2-(Trifluoromethoxy)benzoyl chloride (CAS# 116827-40-8)

2-(Trifluoromethoxy)benzoyl chloride is an organic compound. The following is an introduction to its nature, use, manufacturing methods and safety information:

Quality:
2-(Trifluoromethoxy)benzoyl chloride is a colorless liquid with a pungent odor. It is highly corrosive and can react quickly with water and release hydrogen.

Use:
2-(trifluoromethoxy)benzoyl chloride is an important intermediate in organic synthesis, which is often used as an acylation reagent in organic synthesis reactions.

Method:
The preparation of 2-(trifluoromethoxy)benzoyl chloride is usually obtained by reacting 2-(trifluoromethoxy)benzoic acid with thionyl chloride (SO2Cl2) in an inert solvent. Reaction conditions include the provision of sufficient thionyl chloride and the cooling of the reaction mixture to low temperatures.

Safety Information:
2-(Trifluoromethoxy)benzoyl chloride is an irritating and corrosive compound. Protective gloves, glasses and protective clothing should be worn during operation. Avoid inhaling its vapors and avoid contact with skin and eyes. Store and handle away from open flames and heat sources. In order to avoid the production of toxic gases, it should not be in direct contact with water. Before use or disposal, the corresponding safety operation procedures should be carefully read and observed.