4-(Trifluoromethoxy)benzoic acid（CAS# 330-12-1)
| Hazard Symbols | Xi – Irritant |
| Risk Codes | 36/37/38 – Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 – Wear suitable protective clothing. S37/39 – Wear suitable gloves and eye/face protection |
| WGK Germany | 3 |
| HS Code | 29189900 |
| Hazard Class | IRRITANT |
Introduction
4-(Trifluoromethoxy)benzoic acid is an organic compound. The following is an introduction to its nature, use, preparation method and safety information:
Quality:
- Appearance: 4-(trifluoromethoxy)benzoic acid is a colorless crystalline solid.
- Solubility: Soluble in organic solvents such as ether and methylene chloride.
- Stability: Stable at room temperature, but avoid contact with strong oxidants.
Use:
- 4-(trifluoromethoxy)benzoic acid is commonly used as a reagent in organic synthesis reactions.
- It can be used as a trifluoromethoxy protective group for aromatic aldehyde compounds.
Method:
- There are many preparation methods for 4-(trifluoromethoxy)benzoic acid, and one of the commonly used methods is to react 4-hydroxybenzoic acid with trifluoromethyl alcohol to generate a target product.
Safety Information:
- The dust of 4-(trifluoromethoxy)benzoic acid may be irritating to the respiratory tract and eyes, and inhalation and contact with eyes should be avoided.
- Wear appropriate protective equipment, such as gloves and protective eyewear, when operating.
- When storing and handling, proper laboratory practice and safety manuals should be followed.
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