4′-tert-butyl-4-chlorobutyrophenone（CAS# 43076-61-5)
| Risk Codes | R22 – Harmful if swallowed R41 – Risk of serious damage to eyes R43 – May cause sensitization by skin contact R51/53 – Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
| Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection. S61 – Avoid release to the environment. Refer to special instructions / safety data sheets. S7/8 - S24/25 – Avoid contact with skin and eyes. |
| UN IDs | UN 3077 9/PG 3 |
| WGK Germany | 2 |
Introduction
4 ‘-tert-butyl-4-chlorobutyrophenone, also known as 4′-tert-butyl-4-chlorobutyrophenone, is an organic compound. The following is a detailed description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: 4 ‘-tert-butyl-4-chlorobutyrophenone is a colorless crystal or white crystalline powder.
-Solubility: 4 ‘-tert-butyl-4-chlorobutyrophenone is soluble in common organic solvents such as ethanol, acetone, etc., but has low solubility in water.
-Melting point: The melting point of 4 ‘-tert-butyl-4-chlorobutyrophenone is about 50-52°C.
Use:
- 4 ‘-tert-butyl-4-chlorobutyrophenone can be used as an intermediate in organic synthesis and is widely used in the fields of medicine, pesticide, dye and fragrance.
Preparation Method:
-A commonly used method for preparing 4 ‘-tert-butyl-4-chlorobutyrophenone is to react p-tert-butylbenzophenone with chloroacetic anhydride under alkaline conditions to produce the target compound.
Safety Information:
- 4 ‘-tert-butyl-4-chlorobutyrophenone has low toxicity, but it is still necessary to pay attention to safe use and storage.
-During operation, appropriate protective equipment should be worn to avoid direct contact with skin and eyes.
-Avoid inhaling its dust or vapor, and should be used in a well-ventilated place.
-If you accidentally ingest or come into contact with a large amount of the compound, seek medical attention immediately and carry the appropriate compound label.
