4-Pentyn-1-amine (CAS# 15252-44-5)
Introduction
4-Pentyn-1-amine, also known as 1-pentynamine, is an organic compound. The following is a description of the nature, use, preparation and safety information of 4-Pentyn-1-amine:Nature:
-Appearance: 4-Pentyn-1-amine is a colorless to light yellow liquid.
-Solubility: It is soluble in many organic solvents, such as ethanol and ether.
-Stability: 4-Pentyn-1-amine is relatively stable to oxygen and moisture in the air, but will react with strong oxidants.Use:
- 4-Pentyn-1-amine is an important organic synthesis intermediate, widely used in the synthesis of drugs, dyes, rubber and other chemicals.
-It can be used as a raw material for the synthesis of isoprene adducts, alcohol and ether compounds, ethylene, propylene, etc.
-As an organic synthesis reagent, it is also used in the synthesis of epoxy compounds, ethers, amines, etc.Method:
- 4-Pentyn-1-amine can be prepared by the reaction of valerolactone and ammonia. The valerolactone ring is first opened by acid catalysis to give 1,4-pentanedione. The 1,4-pentanedione is then reacted with potassium hydroxide by heating to produce 4-pentyn-1-one. Finally, 4-pentyn-1-one is reacted by aqueous ammonia to form 4-Pentyn-1-amine.Safety Information:
- 4-Pentyn-1-amine is an irritating compound that may cause eye, skin and respiratory tract irritation. Care should be taken to avoid direct contact during use.
-It is a flammable substance and should be kept away from open flames and heat sources, and away from oxidants.
-It is recommended to wear suitable personal protective equipment, including chemical goggles, protective gloves and protective clothing.
-For accidental exposure or ingestion, please seek medical advice immediately and bring the Material Safety Data Sheet (MSDS) for handling.Please note that the use and handling of 4-Pentyn-1-amine need to be carried out under safe laboratory conditions, and strict compliance with relevant operating procedures and regulations is required.
-Solubility: It is soluble in many organic solvents, such as ethanol and ether.
-Stability: 4-Pentyn-1-amine is relatively stable to oxygen and moisture in the air, but will react with strong oxidants.Use:
- 4-Pentyn-1-amine is an important organic synthesis intermediate, widely used in the synthesis of drugs, dyes, rubber and other chemicals.
-It can be used as a raw material for the synthesis of isoprene adducts, alcohol and ether compounds, ethylene, propylene, etc.
-As an organic synthesis reagent, it is also used in the synthesis of epoxy compounds, ethers, amines, etc.Method:
- 4-Pentyn-1-amine can be prepared by the reaction of valerolactone and ammonia. The valerolactone ring is first opened by acid catalysis to give 1,4-pentanedione. The 1,4-pentanedione is then reacted with potassium hydroxide by heating to produce 4-pentyn-1-one. Finally, 4-pentyn-1-one is reacted by aqueous ammonia to form 4-Pentyn-1-amine.Safety Information:
- 4-Pentyn-1-amine is an irritating compound that may cause eye, skin and respiratory tract irritation. Care should be taken to avoid direct contact during use.
-It is a flammable substance and should be kept away from open flames and heat sources, and away from oxidants.
-It is recommended to wear suitable personal protective equipment, including chemical goggles, protective gloves and protective clothing.
-For accidental exposure or ingestion, please seek medical advice immediately and bring the Material Safety Data Sheet (MSDS) for handling.Please note that the use and handling of 4-Pentyn-1-amine need to be carried out under safe laboratory conditions, and strict compliance with relevant operating procedures and regulations is required.
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