4-Nitrophenylacetic Acid (CAS# 104-03-0)
Application
For organic synthesis.Mainly used in medicine and other organic synthesis, and can also be used for biochemical research
Specification
Appearance yellowish-like powder
Color Beige to yellow
Merck 14,6621
BRN 1911801
pKa 3.85(at 25℃)
PH 2.98 at 22.8℃ and 10g/L
Safety
Hazard Symbols Xi - Irritant
Irritant
Risk Codes 36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
S37/39 - Wear suitable gloves and eye/face protection
UN IDs UN 3077 9 / PGIII
WGK Germany 3
RTECS AJ1130010
TSCA Yes
HS Code 29163900
Hazard Note Irritant
Toxicity dnr-bcs 500 mg/disc MUREAV170,11,86
Packing & Storage
Packed in 25kg/50kg drums. Storage Condition Sealed in dry,Room Temperature
Introduction
4-Nitrophenylacetic acid is a highly versatile and essential chemical used in organic synthesis, mainly in the field of medicine. It is also used in various biochemical research fields. 4-Nitrophenylacetic acid is an effective and widely used building block in the synthesis of numerous drugs and pharmaceuticals. Its unique properties make it an ideal reagent for the creation of potent and selective drugs, which help alleviate diseases and save lives.
4-Nitrophenylacetic Acid is a yellowish-like powder that appears beige to yellow in color. It is an organic synthetic compound that can be used for a wide range of applications in the pharmaceutical and biochemical industries. This chemical is primarily used in organic synthesis, where it serves as a key building block for synthesizing various complex molecules. Its unique properties make it an essential component in the synthesis of many drugs and pharmaceuticals.
4-Nitrophenylacetic acid is a derivative of phenylpropionic acid and consists of a nitro group and a carboxylic acid group attached to a phenyl ring. This chemical is highly soluble in water and other polar solvents. Its unique chemical properties make it an ideal reagent for use in a wide array of organic synthesis procedures, including peptide synthesis, esterification, amidation, and reductive amination.
1. Pharmaceutical Applications:
4-Nitrophenylacetic acid is widely used in the pharmaceutical industry, where it serves as a key building block in the production of various drugs. 4-Nitrophenylacetic acid can be used in the synthesis of drugs for treating anxiety, asthma, cancer, cholesterol, hypertension, inflammation, and mental health disorders, among others.
2. Biochemical Applications:
4-Nitrophenylacetic acid is also widely used in biochemical research, where it serves as a reaction mechanism probe. It can be converted into 4-nitrophenylate derivatives that are used to probe the electron transfer processes in various enzymatic reaction mechanisms. As a result of this probe, 4-nitrophenylacetic acid can be used in the measurement of changes in enzymatic activity when various substrates are introduced.
In conclusion, 4-Nitrophenylacetic acid is a highly versatile and essential chemical used in organic synthesis, especially in the production and development of drugs. 4-Nitrophenylacetic acid is also used in various biochemical research fields, where it helps probe the electron transfer processes in various enzymatic reaction mechanisms. Its excellent physical and chemical properties, such as high solubility in water, make it an invaluable reagent in various organic synthesis procedures. 4-Nitrophenylacetic acid is a game-changer in the pharmaceutical industry, where its use has led to the development of various drugs that have improved and saved countless lives.
