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4-Methylumbelliferone(CAS# 90-33-5)

Chemical Property:

Molecular Formula C10H8O3
Molar Mass 176.17
Density 1.1958 (rough estimate)
Melting Point 188.5-190°C(lit.)
Boling Point 267.77°C (rough estimate)
Water Solubility slightly soluble
Solubility Soluble in ethanol, acetic acid, alkali solution and ammonia, slightly soluble in hot water, ether and chloroform.
Appearance Needle crystallization
Color off-white to yellow
Maximum wavelength(λmax) ['221nm, 251nm, 322nm']
Merck 14,4854
BRN 142217
pKa 7.79(at 25℃)
Storage Condition 2-8°C
Stability Stable. Combustible. Incompatible with strong oxidizing agents.
Refractive Index 1.5036 (estimate)
MDL MFCD00006866
Physical and Chemical Properties Needle-like crystals. Melting point 185-186 °c (194-195 °c) soluble in ethanol, acetic acid, alkali solution and ammonia, slightly soluble in hot water, ether and chloroform. And concentrated sulfuric acid in the role of blue fluorescence.
Use This product is choleretic, and is an intermediate of the anti-allergic drug cromolyn sodium.

Product Detail

Product Tags

Risk Codes R36/37/38 – Irritating to eyes, respiratory system and skin.
R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed.
Safety Description S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39 – Wear suitable gloves and eye/face protection
S36 – Wear suitable protective clothing.
WGK Germany 2
RTECS GN7000000
TSCA Yes
HS Code 29329990
Hazard Note Irritant
Toxicity LD50 oral in rat: 3850mg/kg

 

Introduction

Oxymethocoumarin, also known as vanillone, is an organic compound.

 

Quality:

Appearance: Oxymethaumarin is a white or yellowish crystalline solid with a special aroma, similar to vanilla.

Solubility: Oxymethocoumarin dissolves slightly in hot water, but is almost insoluble in cold water. It is soluble in organic solvents such as ethanol, ether and chloroform.

Chemical properties: Oxymethacoumarin is relatively stable in acidic solution, but it is easy to decompose in strong alkaline solution or high temperature.

 

Use:

 

Method:

Oxymethaumarin can be extracted from natural vanilla and is mainly derived from vanilla herbaceous plants such as vanilla bean or vanilla grass. In addition, it can also be prepared by synthetic methods, usually using natural coumarin as raw material, and transformed through a series of chemical reactions.

 

Safety Information:

Oxymethocoumarin is generally considered safe, but allergic reactions may occur in some people. When it is produced and used in industry, appropriate safety measures should be taken, such as wearing protective gloves and protective glasses. Contact with substances such as strong acids, strong alkalis, and oxidants should be avoided to avoid danger.


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