4-Methylpropiophenone（CAS# 5337-93-9)

Introduction

4-Methylphenylacetone, also known as 4-methylphenylacetone, is an organic compound.

Here are some important properties regarding 4-methylpropionone:

1. Appearance: colorless liquid or white crystal.

2. Density: 0.993g/mLat 25°C(lit.)

5. Solubility: Soluble in organic solvents such as ethanol, ether and benzene.

6. Storage stability: It should be kept away from open flames and oxidants, and stored in a dry, cool and ventilated place.

4-Methylpropiophenone has some uses in certain areas, including:

2. Research use: In organic synthesis, it can be used as a precursor of ketones or alcohols for the synthesis of other organic compounds.

Common methods for the preparation of 4-methylpropiophenone include:

1. Marthet reaction: Styrene and carbon dioxide are reacted in a continuous ring sweep reactor to obtain 4-methylacetophenone, and then 4-methylacetophenone is prepared by oxidation and reduction.

2. Vilsmeier–Haack reaction: Phenylethanol is reacted with nitric acid and phosphine under the reaction conditions of alkylation of alkylloids to obtain 4-methylphenylacetone.

1. Avoid contact with skin, eyes and mucous membranes.

3. Avoid inhaling vapours or mist, and wear appropriate protective gloves, goggles, and protective clothing when using.

5. When storing and handling, avoid contact with flammable substances and store in an airtight container, away from heat sources and open flames.