4-Chloro-7-azaindole(CAS#55052-28-3)
| Risk Codes | R22 – Harmful if swallowed R37/38 – Irritating to respiratory system and skin. R41 – Risk of serious damage to eyes |
| Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 – Wear eye / face protection. |
| UN IDs | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| HS Code | 29339900 |
| Hazard Class | 6.1 |
| Packing Group | Ⅲ |
Introduction
4-chloro-7-azaindole, also known as CNI-13, is an organic compound. The following is an introduction to its nature, use, manufacturing methods and safety information:Quality:- Appearance: White or white-yellow crystalline powder.- Solubility: soluble in organic solvents such as chloroform, dichloromethane, insoluble in water.- Chemical properties: It is a heterocyclic compound with some stability and inertness.Use:- Chemical synthesis: It can be applied to the synthesis reaction of indole compounds.- Pesticides: can be used as raw materials for insecticides or herbicides.Method:The preparation of 4-chloro-7-azaindole can be carried out by the following reactions:- Pyrrole and chloroacetic acid are reacted in the presence of ammonium chloride to produce pyrrole 4-chloro-1-acetic acid.- Then, pyrrole 4-chloro-1-acetic acid is condensed with ammonia and acetaldehyde under alkaline conditions to form 4-chloro-7-azaindole.4. Safety Information:- It has an irritating effect on the eyes and skin, rinse with water immediately after contact.- Appropriate precautions should be taken during use, such as wearing gloves, protective clothing and protective eyewear.- Avoid inhaling dust and ensure that the operation is carried out in a well-ventilated area.- Avoid contact with oxidants and strong acids during storage and use to prevent possible dangerous reactions.
