4-Chloro-4′-hydroxybenzophenone（CAS# 42019-78-3)
| Risk Codes | R36/37/38 – Irritating to eyes, respiratory system and skin. R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | S24/25 – Avoid contact with skin and eyes. S37/39 – Wear suitable gloves and eye/face protection S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 – Wear suitable protective clothing. |
| HS Code | 29144000 |
| Hazard Note | Irritant |
Introduction
4-Chloro-4′-hydroxybenzophenone is an organic compound. The following is information about the properties, uses, preparation methods, and safety of the compound:
Quality:
Appearance: 4-Chloro-4′-hydroxybenzophenone is a white crystalline or crystalline powder.
Solubility: soluble in ethanol, dimethylformamide and chloroform, slightly soluble in ether and carbon chloride.
Use:
4-Chloro-4′-hydroxybenzophenone can be used as an intermediate in organic synthesis for the synthesis of other organic compounds.
Method:
4-Chloro-4′-hydroxybenzophenone can be obtained by substitution of sodium sulfite with sodium thiothioreagent (e.g., phthathiadine) of sodium sulfite. The specific preparation method is as follows:
The phthamethamidine is dissolved in dimethylformamide, hydroxyacetophenone is added to the reaction solution, after a certain period of reaction, water is added, and the product is extracted, dried and crystallized with chloroform to obtain the target product.
Safety Information:
4-Chloro-4′-hydroxybenzophenone is relatively stable under general conditions. However, contact with strong oxidizing agents should be avoided.
Appropriate personal protective equipment such as gloves, goggles, and gowns should be worn when performing such operations.
It should be kept away from combustible substances and heat sources, and stored in an airtight container to avoid exposure to air.
Please dispose of the compound and its waste properly, following local waste management regulations.
