4-Chloro-4′-fluorobutyrophenone（CAS# 3874-54-2)
| Risk Codes | R22 – Harmful if swallowed R36/37/38 – Irritating to eyes, respiratory system and skin. R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | S24/25 – Avoid contact with skin and eyes. S36 – Wear suitable protective clothing. S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| TSCA | Yes |
| Hazard Note | Irritant |
Introduction
4-Chloro-4′-fluorobutanone is an organic compound. The following is a presentation on the properties, uses, preparation methods, and safety information of this compound:
Quality:
- Appearance: 4-Chloro-4′-fluorophenone is a colorless or light yellow liquid.
- Solubility: It can be dissolved in some organic solvents such as chloroform, alcohols, and ethers.
Use:
- In agriculture, it can be used to produce pesticides and fungicides.
Method:
- 4-Chloro-4′-fluorobutanone can be prepared by the reaction of phenylbutanone with chlorine and fluorine compounds.
- A common preparation method is to prepare 4-chlorophenone by reaction of phenylbutanone and hydrogen chloride, and then by hydrogen fluoride reaction to obtain 4-chloro-4′-fluorobutanone. The reaction is usually carried out at the appropriate temperature and pressure.
Safety Information:
- 4-Chloro-4′-fluorobutanone is a chemical that should be used in accordance with appropriate safety handling protocols, such as wearing protective gloves, goggles, and protective clothing.
- During the procedure, avoid inhaling its vapors or coming into contact with the skin and eyes.
- Seek immediate medical attention when ingested, inhaled, or in contact with skin to skin and provide the chemical’s Safety Data Sheet to your physician for reference.
When using any chemical, it is important to follow proper handling and safety guidance and take appropriate measures on a case-by-case basis.
