4′-Chloro-2′-hydroxyacetophenone(CAS#6921-66-0)
| Hazard Symbols | Xn – Harmful |
| Risk Codes | R22 – Harmful if swallowed R37/38 – Irritating to respiratory system and skin. R41 – Risk of serious damage to eyes |
| Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 – Wear eye / face protection. |
Introduction
4 ‘-Chloro-2′-hydroxyacetophenone is an organic compound with the formula C8H7ClO2 and a molecular weight of 170.59g/mol. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
- 4 ‘-Chloro-2′-hydroxyacetophenone is a white crystalline solid.
-It is stable at room temperature and not volatile.
-The compound is insoluble in water, but soluble in organic solvents such as ethanol, ether and chloroform.
Use:
- 4 ‘-Chloro-2′-hydroxyacetophenone is used as an important intermediate in organic synthesis.
-It can be used to synthesize other organic compounds, such as drugs, dyes and pesticides.
-The compound also has biological activities such as antibacterial, antioxidant and anti-inflammatory, so it is also used in the field of medicine.
Preparation Method:
The synthesis method of -4 ‘-Chloro-2′-hydroxyacetophenone can be achieved by the hydrochloric acid esterification reaction of benzophenone, and then the hydroxylation reaction.
-Specific synthetic methods can be consulted in chemical synthesis manuals or professional research papers.
Safety Information:
- 4 ‘-Chloro-2′-hydroxyacetophenone has low toxicity, but attention should be paid to rational use and storage.
-Wear appropriate personal protective equipment such as gloves and goggles when using.
-Avoid direct contact with skin and eyes, and avoid inhalation or ingestion of the compound.
-When using or storing, keep it away from fire and high temperature environment.
-If it enters the eyes or skin by accident, rinse immediately with plenty of water and seek medical help. If ingested by accident, seek medical attention promptly.
