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4-Chloro-1H-indole(CAS# 25235-85-2)

Chemical Property:

Molecular Formula C8H6ClN
Molar Mass 151.59
Density 1.259 g/mL at 25 °C (lit.)
Boling Point 129-130 °C/4 mmHg (lit.)
Flash Point >230°F
Water Solubility insoluble
Solubility ethanol: soluble50mg/mL, clear, colorless
Vapor Presure 0.00309mmHg at 25°C
Appearance liquid (clear)
Specific Gravity 1.259
Color clear yellow
BRN 114880
pKa 16.10±0.30(Predicted)
Storage Condition 2-8°C
Stability Store in Refrigerator
Refractive Index n20/D 1.628(lit.)

Product Detail

Product Tags

Risk Codes R36/37/38 – Irritating to eyes, respiratory system and skin.
R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed.
Safety Description S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 – Wear suitable protective clothing.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany 3
FLUKA BRAND F CODES 10
HS Code 29339990
Hazard Class IRRITANT

 

Introduction

4-Chloroindole is an organic compound. The following is an introduction to the properties, uses, preparation methods and safety information of 4-chloroindole:

 

Quality:

- Appearance: 4-chloroindole is a white to light yellow crystalline solid.

- Solubility: Soluble in common organic solvents, such as ethanol, ether and dimethyl sulfoxide.

- Stability: Stable in dry conditions, but easily decomposes in moisture.

 

Use:

- 4-chloroindole can be used as an intermediate in organic synthesis for the synthesis of other organic compounds.

- In medical research, 4-chloroindole is also used as a tool to study cancer cells and the nervous system.

 

Method:

- A commonly used method for the preparation of 4-chloroindole is by chlorinating indole. Indole reacts with ferrous chloride or aluminum chloride to form 4-chloroindole.

- Specific reaction conditions and reaction systems can be adjusted as needed.

 

Safety Information:

- 4-Chloroindole is toxic and requires appropriate safety measures such as wearing protective gloves, safety glasses, and protective masks when handling.

- Avoid contact with skin and eyes, and make sure to operate in a well-ventilated area.

- In case of aspiration or ingestion, seek medical attention immediately.

 


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