4-Bromo-3-fluorotoluene（CAS# 452-74-4)
| Hazard Symbols | Xi – Irritant |
| Risk Codes | R10 – Flammable R36/37/38 – Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 – Wear suitable gloves and eye/face protection S16 – Keep away from sources of ignition. |
| UN IDs | UN 1993 3/PG 3 |
| WGK Germany | 3 |
| HS Code | 29039990 |
| Hazard Note | Irritant |
| Hazard Class | 3 |
| Packing Group | III |
Introduction
4-Bromo-3-fluorotoluene is an organic compound. The following is an introduction to its properties, uses, manufacturing methods and safety information:
Quality:
4-Bromo-3-fluorotoluene is a colorless liquid with a benzene ring structure and bromine and fluorine substituents. It has a pungent odor at room temperature. It is poorly soluble in cold water but can be dissolved in organic solvents.
Use:
4-Bromo-3-fluorotoluene is an important intermediate in organic synthesis. It is also commonly used in the field of materials, for example for the synthesis of polymers with special properties.
Method:
The preparation of 4-bromo-3-fluorotoluene is achieved by reacting hydrogen fluoride (HF) and hydrogen bromide (HBr) with appropriate toluene-based compounds in a reaction system. This reaction needs to be carried out at the right temperature and pressure and using an acidic catalyst.
Safety Information:
4-Bromo-3-fluorotoluene is a toxic compound and should be avoided from direct contact with the skin, eyes, and respiratory tract. When in use, appropriate protective equipment such as gloves, goggles, and a protective face shield should be worn. When handling this compound, proper laboratory safety operating procedures should be followed and operated in a well-ventilated environment. It should be stored in a dry, cool and well-ventilated place, away from fire sources and open flames. Any operation using the compound should be carried out with suitable equipment and conditions, with appropriate training and personnel who understand safe operation.
