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4-Bromo-2-fluorobenzyl bromide (CAS# 76283-09-5)

Chemical Property:

Molecular Formula C7H5Br2F
Molar Mass 267.92
Density 1.9094 (rough estimate)
Melting Point 33-36 °C (lit.)
Boling Point 126 °C (19 mmHg)
Flash Point 126°C/9mm
Vapor Presure 0.0281mmHg at 25°C
Appearance Bright yellow crystal
Color White to off-white
BRN 4307676
Storage Condition under inert gas (nitrogen or Argon) at 2-8°C
Sensitive Lachrymatory
Refractive Index 1.5770 (estimate)
MDL MFCD00055467
Physical and Chemical Properties Melting point 30 ℃, boiling point 126 ℃/2.54kPa.
Use For pharmaceutical synthesis

Product Detail

Product Tags

Hazard Symbols C – Corrosive
Risk Codes R22 – Harmful if swallowed
R34 – Causes burns
R52/53 – Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
R20/21/22 – Harmful by inhalation, in contact with skin and if swallowed.
Safety Description S26 – In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 – Wear suitable protective clothing, gloves and eye/face protection.
S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S61 – Avoid release to the environment. Refer to special instructions / safety data sheets.
UN IDs UN 2923 8/PG 3
WGK Germany 2
HS Code 29039990
Hazard Note Corrosive/Lachrymatory
Hazard Class 8
Packing Group III

 

Introduction

2-Fluoro-4-bromobenzyl bromide is an organic compound. The following is an introduction to its nature, use, preparation method and safety information:

 

Quality:

- Appearance: 2-Fluoro-4-bromobenzyl bromide is a colorless to pale yellow liquid.

- Solubility: It is soluble in organic solvents such as alcohols and ethers, but insoluble in water.

 

Use:

- 2-Fluoro-4-bromobenzyl bromide is often used as an important intermediate in organic synthesis.

- This compound can also be used as a raw material for catalysts and surfactants.

 

Method:

The preparation method of 2-fluoro-4-bromobenzyl bromide is as follows:

- Reaction of 2-bromobenzyl alcohol with 2,4-difluorobenzoic acid, catalyzed by alkali, at the appropriate temperature and time conditions.

- After the reaction is completed, purification and separation are carried out by crystallization or distillation to obtain 2-fluoro-4-bromobenzyl bromide with high purity.

 

Safety Information:

- 2-Fluoro-4-bromobenzyl bromide is a volatile organic compound and its vapours should be avoided by inhalation.

- Wear appropriate personal protective equipment such as protective glasses, gloves and lab coats during handling and handling.

- When storing and using, avoid contact with oxidants, strong acids, strong alkalis and other substances to avoid dangerous reactions.

- When storing and disposing of it, relevant laws, regulations and safety regulations should be observed.


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