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4-Bromo-2-fluoroaniline(CAS#367-24-8)

Chemical Property:

Molecular Formula C6H4BrF2N
Molar Mass 208
Density 1.788±0.06 g/cm3(Predicted)
Melting Point 74-78 °C (lit.)
Boling Point 212.1±35.0 °C(Predicted)
Flash Point 62.8°C
Vapor Presure 1.62mmHg at 25°C
Appearance White crystal
BRN 4741102
pKa 1.48±0.10(Predicted)
Storage Condition Keep in dark place,Sealed in dry,Room Temperature
Refractive Index 1.52
MDL MFCD00010221
Physical and Chemical Properties melting point 39-42°C
boiling point 103-108°C (13 mmHg)
flash point 104°C

Product Detail

Product Tags

Risk Codes R25 – Toxic if swallowed
R36/37/38 – Irritating to eyes, respiratory system and skin.
Safety Description S28 – After contact with skin, wash immediately with plenty of soap-suds.
S45 – In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs UN 2811 6.1/PG 3
WGK Germany 3
HS Code 29214200
Hazard Class IRRITANT

 

Introduction

4-Bromo-2-fluoroaniline is an organic compound with the formula C6H5BrFN. The following is a description of its nature, use, preparation and safety information:

 

Nature:

-Appearance: 4-Bromo-2-fluoroaniline is a white to pale yellow solid.

-Solubility: Soluble in organic solvents such as ethanol and dimethylformamide, insoluble in water.

 

Use:

-Chemical synthesis: 4-Bromo-2-fluoroaniline is an important intermediate, which is widely used in the synthesis of drugs and pesticides.

-Organic synthesis: It can be used as a fluorinating agent for fluorination reactions in organic synthesis.

 

Preparation Method:

4-Bromo-2-fluoroaniline is generally synthesized by the following steps:

1. using aniline as raw material, using oxidation reagent to oxidize aniline to phenol.

2. 4-bromophenol is obtained by bromination of phenol.

3. 4-Bromophenol is reacted with a fluorinating reagent to form 4-Bromo-2-fluoroaniline.

 

Safety Information:

- 4-Bromo-2-fluoroaniline is a chemical and must be used in accordance with safety procedures.

-It may be irritating to the eyes, skin and respiratory tract, so wear appropriate personal protective equipment when using it.

-Avoid breathing gas, eating or touching skin. If contact occurs, immediately flush the affected area with water and seek medical help.

-During storage and transportation, it should be kept isolated from other substances, and the packaging should be properly sealed, away from fire and heat sources.

 

Please note that the above information is for reference only. Please read the product label and technical instructions carefully during specific operation and use, and follow relevant safety instructions.


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